Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Tryptophan. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.91 |
| ▸ | MAPT | P10636 | 3/20 | 0.91 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.91 |
| ▸ | LMNA | P02545 | 2/20 | 0.91 |
| ▸ | TSHR | P16473 | 2/20 | 0.91 |
| ▸ | BLM | P54132 | 2/20 | 0.91 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.91 |
| ▸ | MEN1 | O00255 | 2/20 | 0.91 |
| ▸ | MPO | P05164 | 1/20 | 0.91 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.91 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | APAF1 | O14727 | 1/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | HTR2A | P28223 | 3/20 | 0.63 |
| ▸ | HTR1A | P08908 | 2/20 | 0.63 |
| ▸ | HTR2C | P28335 | 2/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dl-Tryptophan SCHEMBL28298000 | 1.00 | KDM4E (0.91) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL28001586 | 1.00 | KDM4E (0.91) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL27748750 | 0.96 | KDM4E (0.94) | KDM4EMAPTKMT2ALMNATSHR | |
| Tryptophan SCHEMBL27748748 | 0.96 | KDM4E (0.94) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL28580277 | 0.96 | KDM4E (0.94) | KDM4EMAPTKMT2ALMNATSHR | |
| Tryptophan SCHEMBL23141133 | 0.96 | KMT2A (1.00) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL7327 | 0.96 | KMT2A (1.00) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL19161120 | 0.96 | KMT2A (1.00) | KDM4EMAPTKMT2ALMNATSHR | |
| Tryptophan SCHEMBL475350 | 0.96 | KMT2A (1.00) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL4732052 | 0.96 | KMT2A (1.00) | KDM4EMAPTKMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095128-B1 | AMINE REACTION COMPOUNDS COMPRISING ONE OR MORE ACTIVE INGREDIENT | PROCTER & GAMBLE (US) | 2005-04-20 | — | — | EP | claimed |
| US-20050009727-A1 | Laundry and cleaning compositions | THE PROCTER & GAMBLE COMPANY (US) | 2005-01-13 | — | — | US | claimed |
| US-20040116320-A1 | Laundry and cleaning compositions | THE PROCTER & GAMBLE COMPANY (US) | 2004-06-17 | — | — | US | claimed |
| US-20030211963-A1 | Laundry and cleaning compositions | THE PROCTER & GAMBLE COMPANY | 2003-11-13 | — | — | US | claimed |
| US-20030064899-A1 | Amine reaction compounds comprising one or more active ingredient | THE PROCTER & GAMBLE COMPANY | 2003-04-03 | — | — | US | claimed |
| EP-1144566-A2 | LAUNDRY AND CLEANING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2001-10-17 | — | — | EP | claimed |
| EP-1095128-A1 | AMINE REACTION COMPOUNDS COMPRISING ONE OR MORE ACTIVE INGREDIENT | THE PROCTER & GAMBLE COMPANY (US) | 2001-05-02 | — | — | EP | claimed |
| WO-2000002991-A1 | AMINE REACTION COMPOUNDS COMPRISING ONE OR MORE ACTIVE INGREDIENT | THE PROCTER & GAMBLE COMPANY (US) | 2000-01-20 | — | — | WO | claimed |
| WO-2000002981-A2 | LAUNDRY AND CLEANING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2000-01-20 | — | — | WO | claimed |
| EP-0971024-A1 | Laundry and cleaning compositions | THE PROCTER & GAMBLE COMPANY (US) | 2000-01-12 | — | — | EP | claimed |
| EP-0971025-A1 | Amine reaction compounds comprising one or more active ingredient | THE PROCTER & GAMBLE COMPANY (US) | 2000-01-12 | — | — | EP | claimed |
| US-20240206461-A1 | DELIVERY PARTICLES WITH HIGH CORE:WALL RATIOS | ENCAPSYS, LLC (US) | 2024-06-27 | — | — | US | disclosed |
| US-12016963-B2 | Freshening compositions with alkoxylated phenols | THE PROCTER & GAMBLE COMPANY (US) | 2024-06-25 | — | — | US | disclosed |
| EP-4370644-A1 | CONSUMER PRODUCTS COMPRISING DELIVERY PARTICLES WITH HIGH CORE:WALL RATIOS | The Procter & Gamble Company (US) | 2024-05-22 | — | — | EP | disclosed |
| EP-4369931-A2 | DELIVERY PARTICLES WITH HIGH CORE:WALL RATIOS | Encapsys, LLC (US) | 2024-05-22 | — | — | EP | disclosed |
| WO-2000002991-A1 | AMINE REACTION COMPOUNDS COMPRISING ONE OR MORE ACTIVE INGREDIENT | THE PROCTER & GAMBLE COMPANY (US) | 2000-01-20 | — | — | WO | disclosed |
| WO-2000002981-A2 | LAUNDRY AND CLEANING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2000-01-20 | — | — | WO | disclosed |
| EP-0971021-A1 | Process for producing particles of amine reaction product | THE PROCTER & GAMBLE COMPANY (US) | 2000-01-12 | — | — | EP | disclosed |
| EP-0971024-A1 | Laundry and cleaning compositions | THE PROCTER & GAMBLE COMPANY (US) | 2000-01-12 | — | — | EP | disclosed |
| EP-0971025-A1 | Amine reaction compounds comprising one or more active ingredient | THE PROCTER & GAMBLE COMPANY (US) | 2000-01-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240206461-A1 | DELIVERY PARTICLES WITH HIGH CORE:WALL RATIOS | CETP, CHMP4B, HDLBP | ADRA2A 1453/4885KDM4E 2355/4885MAPT 576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.