SCHEMBL4530128

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1882625	0.83	MAP4K4 (0.57)	DHFRHEXAHEXBSMN1; SMN2RAB9A
	SCHEMBL12368259	0.83	HEXA (0.68)	DHFRHEXAHEXBALDH1A1RAB9A
	Hydrochloric Acid SCHEMBL4532657	0.79	HEXA (0.48)	DHFRHEXAHEXBRAB9A
	SCHEMBL3500167	0.79	DHFR (0.61)	DHFRHEXAHEXBKDM4ESMN1; SMN2
	SCHEMBL4532674	0.77	NPC1 (0.43)	DHFRHEXAHEXBRAB9ANPC1
	Hydrochloric Acid SCHEMBL4518745	0.76	NPC1 (0.42)	DHFRHEXAHEXBRAB9ANPC1
	SCHEMBL7165985	0.76	HRH4 (0.50)	IKBKBKMT2AHRH3
	SCHEMBL6049535	0.75	IKBKB (0.56)	IKBKBDHFRHEXAHEXBKDM4E
	SCHEMBL4539404	0.75	HEXA (0.44)	DHFRHEXAHEXB
	SCHEMBL17495238	0.73	IKBKB (0.56)	IKBKBKDM4ESMN1; SMN2RXFP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.