SCHEMBL4530355

SCHEMBL4530355

CCCCCC[Si](O)(O)CN

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 8/20 0.43
TSHR P16473 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
ALDH1A1 P00352 2/20 0.43
EPHX1 P07099 2/20 0.43
THRB P10828 1/20 0.40
LMNA P02545 2/20 0.38
HSD17B10 Q99714 1/20 0.38
SPHK2 Q9NRA0 1/20 0.36
SPHK1 Q9NYA1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9622316 0.84 TSHR (0.50) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL1686890 0.84 TSHR (0.50) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL1686433 0.84 TSHR (0.50) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL1686608 0.84 TSHR (0.50) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL1686556 0.84 TSHR (0.50) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL1686462 0.84 TSHR (0.50) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL1686845 0.84 TSHR (0.50) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL1686598 0.84 TSHR (0.50) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL838158 0.81 TSHR (0.44) TSHRMEN1KMT2AALDH1A1EPHX1
SCHEMBL4523704 0.79 DNM1 (0.44) DNM1TSHRMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7507480-B2 Corrosion-resistant metal surfaces BROOKHAVEN SCIENCE ASSOCIATES, LLC (US) 2009-03-24 US disclosed
US-20060269760-A1 Corrosion-resistant metal surfaces ENERGY, UNITED STATES DEPARTMENT OF 2006-11-30 US disclosed