SCHEMBL4530360

SCHEMBL4530360

CCCCCC(CN)[SiH](O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 2/20 0.43
OPRM1 P35372 1/20 0.41
CYP2D6 P10635 2/20 0.41
HTT P42858 2/20 0.41
LMNA P02545 2/20 0.41
TP53 P04637 2/20 0.41
GMNN O75496 1/20 0.41
POLB P06746 1/20 0.41
THPO P40225 1/20 0.41
MTOR P42345 1/20 0.41
BLM P54132 1/20 0.41
KDM4E B2RXH2 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPT P10636 1/20 0.41
CETP P11597 1/20 0.41
UBE2N P61088 1/20 0.41
FDPS P14324 4/20 0.40
GPR84 Q9NQS5 3/20 0.39
FFAR1 O14842 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4525744 0.77 S1PR2 (0.50) SPHK1OPRM1CYP2D6HTTLMNA
SCHEMBL4522719 0.77 S1PR2 (0.50) SPHK1OPRM1CYP2D6HTTLMNA
SCHEMBL4527181 0.76 DNM1 (0.39) SPHK1ALDH1A1
SCHEMBL4522710 0.74 DNM1 (0.42) SPHK1CYP2D6LMNAGMNNPOLB
SCHEMBL4303715 0.73
SCHEMBL4171750 0.73
SCHEMBL2357309 0.73
SCHEMBL11676992 0.71 HTT (0.55) SPHK1CYP2D6HTTLMNATP53
SCHEMBL16390108 0.71 HTT (0.55) SPHK1CYP2D6HTTLMNATP53
SCHEMBL16390390 0.71 HTT (0.55) SPHK1CYP2D6HTTLMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7507480-B2 Corrosion-resistant metal surfaces BROOKHAVEN SCIENCE ASSOCIATES, LLC (US) 2009-03-24 US disclosed
US-20060269760-A1 Corrosion-resistant metal surfaces ENERGY, UNITED STATES DEPARTMENT OF 2006-11-30 US disclosed