Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4539935 | 0.99 | TLR7 (0.56) | TLR7TLR8 | |
| SCHEMBL4528277 | 0.91 | TLR7 (0.60) | TLR7TLR8 | |
| SCHEMBL4530654 | 0.88 | TLR7 (0.57) | TLR7TLR8 | |
| SCHEMBL13963123 | 0.83 | TLR7 (0.54) | TLR7TLR8 | |
| SCHEMBL4530219 | 0.80 | TLR7 (0.55) | TLR7TLR8 | |
| SCHEMBL4519524 | 0.80 | TLR7 (0.51) | TLR7TLR8 | |
| SCHEMBL5823068 | 0.80 | TLR7 (0.51) | TLR7TLR8 | |
| SCHEMBL4530677 | 0.80 | TLR7 (0.55) | TLR7TLR8 | |
| SCHEMBL4519615 | 0.79 | TLR7 (0.64) | TLR7TLR8 | |
| Iodide SCHEMBL4531197 | 0.79 | TLR7 (0.64) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8802853-B2 | Arylalkenyl and arylalkynyl substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-08-12 | — | — | US | disclosed |
| US-20090030030-A1 | ARYLALKENYL AND ARYLALKYNYL SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY | 2009-01-29 | — | — | US | disclosed |
| EP-1701955-A1 | ARYLALKENYL AND ARYLALKYNYL SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2006-09-20 | — | — | EP | disclosed |
| WO-2005066170-A1 | ARYLALKENYL AND ARYLALKYNYL SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-07-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030030-A1 | ARYLALKENYL AND ARYLALKYNYL SUBSTITUTED IMIDAZOQUINOLINES | IL2, IFNG, IRF3 | TLR7 67/4885TLR8 157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.