Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL453157 | 1.00 | ALOX5 (0.55) | ALOX5ALDH1A1PKMLMNAHPGD | |
| SCHEMBL453158 | 1.00 | ALOX5 (0.55) | ALOX5ALDH1A1PKMLMNAHPGD | |
| SCHEMBL4944707 | 0.80 | ALOX5 (0.50) | ALOX5ALDH1A1PKMLMNAHPGD | |
| SCHEMBL4944708 | 0.80 | ALOX5 (0.50) | ALOX5ALDH1A1PKMLMNAHPGD | |
| SCHEMBL3009798 | 0.80 | ALOX5 (0.50) | ALOX5ALDH1A1PKMLMNAHPGD | |
| SCHEMBL348443 | 0.80 | ALOX5 (0.50) | ALOX5ALDH1A1PKMLMNAHPGD | |
| SCHEMBL348444 | 0.80 | ALOX5 (0.50) | ALOX5ALDH1A1PKMLMNAHPGD | |
| SCHEMBL3069141 | 0.80 | ALOX5 (0.58) | ALOX5ALDH1A1LMNAHTTMEN1 | |
| SCHEMBL1285898 | 0.80 | ALOX5 (0.58) | ALOX5ALDH1A1PKMLMNAHPGD | |
| SCHEMBL1708187 | 0.80 | ALOX5 (0.58) | ALOX5ALDH1A1PKMLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616169-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | Natrix Separations Inc. (CA) | 2013-07-24 | — | — | EP | claimed |
| WO-2012037101-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | NATRIX SEPARATIONS INC. (CA) | 2012-03-22 | — | — | WO | claimed |
| EP-2616169-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | Natrix Separations Inc. (CA) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012037101-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | NATRIX SEPARATIONS INC. (CA) | 2012-03-22 | — | — | WO | disclosed |
| US-20120064601-A1 | Chromatography Membranes for the Purification of Chiral Compounds | NATRIX SEPARATIONS INC. (CA) | 2012-03-15 | — | — | US | disclosed |