Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 4/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | LHCGR | P22888 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CEL | P19835 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132129 | 0.85 | F2 (0.37) | F2PRSS1ALDH1A1ALDH2NOTUM | |
| Ethylene Glycol SCHEMBL10416141 | 0.76 | F2 (0.35) | F2PRSS1ALDH1A1 | |
| SCHEMBL2059857 | 0.75 | ALDH2 (0.34) | GABRA1F2PRSS1GABRG2GABRB3 | |
| SCHEMBL9009389 | 0.75 | ERN1 (0.36) | F2PRSS1 | |
| SCHEMBL5088751 | 0.69 | F2 (0.33) | F2PRSS1ALDH1A1ALDH2 | |
| SCHEMBL1861133 | 0.69 | F2 (0.33) | F2PRSS1ALDH1A1 | |
| SCHEMBL212973 | 0.67 | KMT2A (0.34) | ALDH1A1 | |
| SCHEMBL209608 | 0.67 | CA1 (0.37) | ALDH1A1 | |
| SCHEMBL2111856 | 0.67 | MAOA (0.37) | POLB | |
| SCHEMBL4649342 | 0.67 | NPC1 (0.36) | GABRA1GABRB2GABRG2GABRB3NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120064088-A1 | METHODS OF TREATING ANEURYSM | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-03-15 | — | — | US | disclosed |
| WO-2011133687-A2 | METHODS AND COMPOSITIONS FOR INHIBITION OF BETA2-ADRENERGIC RECEPTOR DEGRADATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-10-27 | — | — | WO | disclosed |