Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13918341 | 0.96 | CYSLTR2 (0.70) | CYSLTR2POLBRAB9AMAPTNPC1 | |
| SCHEMBL13918511 | 0.94 | CYSLTR2 (0.62) | CYSLTR2POLBRAB9AMAPTNPC1 | |
| SCHEMBL4521894 | 0.91 | CYSLTR2 (0.78) | CYSLTR2POLBRAB9AMAPTNPC1 | |
| SCHEMBL13918382 | 0.90 | CYSLTR2 (0.66) | CYSLTR2POLBRAB9AMAPTNPC1 | |
| SCHEMBL13932995 | 0.89 | CYSLTR2 (0.75) | CYSLTR2POLBRAB9AMAPTNPC1 | |
| SCHEMBL4524350 | 0.89 | CYSLTR2 (0.74) | CYSLTR2POLBRAB9AMAPTNPC1 | |
| SCHEMBL4509893 | 0.87 | CYSLTR2 (0.82) | CYSLTR2POLBNPC1ALDH1A1MEN1 | |
| SCHEMBL13918513 | 0.87 | CYSLTR2 (0.82) | CYSLTR2POLBNPC1ALDH1A1MEN1 | |
| SCHEMBL4521068 | 0.85 | CYSLTR2 (0.52) | CYSLTR2RAB9AMAPTALDH1A1PPARG | |
| SCHEMBL4521070 | 0.85 | CYSLTR2 (0.52) | CYSLTR2RAB9AMAPTALDH1A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498460-B2 | Isophthalic acid derivatives | BAYER HEALTHCARE AG (DE) | 2009-03-03 | — | — | US | disclosed |
| US-20060154912-A1 | Isophtalic acid derivatives | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154912-A1 | Isophtalic acid derivatives | VHL, FABP3, CPT1A | CYSLTR2 1426/4885POLB 2956/4885RAB9A 3779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.