SCHEMBL4533846

SCHEMBL4533846

O=C(O)CCCOP(=O)(O)O

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 8/20 0.50
LPAR2 Q9HBW0 6/20 0.50
LPAR1 Q92633 4/20 0.50
ALDH1A1 P00352 1/20 0.46
LMNA P02545 2/20 0.46
SLC22A6 Q4U2R8 1/20 0.46
TSHR P16473 2/20 0.43
NFKB1 P19838 1/20 0.43
PMP22 Q01453 1/20 0.43
PGK1 P00558 1/20 0.40
PGK2 P07205 1/20 0.40
MVD P53602 1/20 0.40
CAMK2A Q9UQM7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11386950 0.98 LPAR3 (0.48) LPAR3LPAR2LPAR1ALDH1A1LMNA
SCHEMBL21121925 0.93 ALDH1A1 (0.56) LPAR3LPAR2LPAR1ALDH1A1LMNA
SCHEMBL4535481 0.91 ALDH1A1 (0.59) LPAR3LPAR2LPAR1ALDH1A1LMNA
SCHEMBL4536951 0.91 ALDH1A1 (0.59) LPAR3LPAR2LPAR1ALDH1A1LMNA
SCHEMBL4520895 0.91 ALDH1A1 (0.59) LPAR3LPAR2LPAR1ALDH1A1LMNA
SCHEMBL10545856 0.91 ALDH1A1 (0.54) LPAR3LPAR2LPAR1ALDH1A1LMNA
SCHEMBL4516204 0.91 ALDH1A1 (0.59) LPAR3LPAR2LPAR1ALDH1A1LMNA
SCHEMBL4517953 0.91 ALDH1A1 (0.59) LPAR3LPAR2LPAR1ALDH1A1LMNA
SCHEMBL4529208 0.91 ALDH1A1 (0.59) LPAR3LPAR2LPAR1ALDH1A1LMNA
SCHEMBL4525157 0.91 ALDH1A1 (0.59) LPAR3LPAR2LPAR1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2872514-B1 IMIDAZOTRIAZINECARBONITRILES USEFUL AS KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2017-08-30 EP claimed
EP-4605393-A1 TRIAZOLE-SUBSTITUTED IMIDAZO[1,2-A]PYRIMIDINES AS CGAS INHIBITORS GlaxoSmithKline Intellectual Property Development Limited (GB) 2025-08-27 EP disclosed
WO-2025095130-A1 BATTERY PACK AND SPACER 三菱ケミカル株式会社 2025-05-08 WO disclosed
WO-2024083773-A1 TRIAZOLE-SUBSTITUTED IMIDAZO[1,2-A]PYRIMIDINES AS CGAS INHIBITORS GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2024-04-25 WO disclosed
US-11788055-B2 Materials and methods for controlling oxidation and reduction in biosynthetic pathways of species of the genera ralstonia and cupriavidus and organisms related thereto INV NYLON CHEMICALS AMERICAS, LLC (US) 2023-10-17 US disclosed
CN-113423685-A Prodrug modulators of integrated stress pathways 卡里科生命科学有限责任公司 2021-09-21 CN disclosed
EP-3681504-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE Icagen, Inc. (US) 2020-07-22 EP disclosed
CN-104685058-B Microorganisms and methods for making 4-hydroxybutyrate, 1, 4-butanediol, and related compounds 基因组股份公司 2020-07-07 CN disclosed
US-20190338375-A1 MATERIALS AND METHODS FOR CONTROLLING OXIDATION AND REDUCTION IN BIOSYNTHETIC PATHWAYS OF SPECIES OF THE GENERA RALSTONIA AND CUPRIAVIDUS AND ORGANISMS RELATED THERETO INV NYLON CHEMICALS AMERICAS, LLC 2019-11-07 US disclosed
WO-2019055754-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN, INC. (US) 2019-03-21 WO disclosed
EP-2872514-A1 IMIDAZOTRIAZINECARBONITRILES USEFUL AS KINASE INHIBITORS Bristol-Myers Squibb Company (US) 2015-05-20 EP disclosed
WO-2014011974-A1 IMIDAZOTRIAZINECARBONITRILES USEFUL AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2014-01-16 WO disclosed
CN-102625845-A Microorganisms and methods for the synergistic production of isopropanol and primary alcohols, glycols and acids GENOMATICA INC 2012-08-01 CN disclosed
US-20090220431-A1 MAGNETIC RESONANCE IMAGING CONTRAST AGENTS CONTAINING WATER-SOLUBLE NANOPARTICLES OF MANGANESE OXIDE OR MANGANESE METAL OXIDE INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2009-09-03 US disclosed
WO-2007064175-A1 MAGNETIC RESONANCE IMAGING CONTRAST AGENTS CONTAINING WATER-SOLUBLE NANOPARTICLES OF MANGANESE OXIDE OR MANGANESE METAL OXIDE INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2007-06-07 WO disclosed