SCHEMBL4533937

SCHEMBL4533937

OC(Cl)CCBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10103919 0.80
SCHEMBL10112607 0.80
SCHEMBL483389 0.76
SCHEMBL13626156 0.76
SCHEMBL2080052 0.72
SCHEMBL14915979 0.71
SCHEMBL18533315 0.69
SCHEMBL3332382 0.69 ALDH1A1 (0.41)
SCHEMBL6048310 0.69
SCHEMBL7138282 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3026049-B1 METHOD FOR PREPARING BENZAMIDE DERIVATIVE, NOVEL INTERMEDIATE USED IN PREPARATION OF BENZAMIDE, AND METHOD FOR PREPARING NOVEL INTERMEDIATE DONG A ST CO LTD (KR) 2021-09-22 EP disclosed
US-9771348-B2 Method for preparing benzamide derivative, novel intermediate used in preparation of benzamide, and method for preparing novel intermediate DONG-A ST CO., LTD (KR) 2017-09-26 US disclosed
US-20160185751-A1 METHOD FOR PREPARING BENZAMIDE DERIVATIVE, NOVEL INTERMEDIATE USED IN PREPARATION OF BENZAMIDE, AND METHOD FOR PREPARING NOVEL INTERMEDIATE DONG-A ST CO., LTD (KR) 2016-06-30 US disclosed
EP-3026049-A1 METHOD FOR PREPARING BENZAMIDE DERIVATIVE, NOVEL INTERMEDIATE USED IN PREPARATION OF BENZAMIDE, AND METHOD FOR PREPARING NOVEL INTERMEDIATE Dong-A ST Co., Ltd. (KR) 2016-06-01 EP disclosed
CN-105636946-A Method for preparing benzamide derivative, novel intermediate used in preparation of benzamide, and method for preparing novel intermediate DONG A ST CO LTD 2016-06-01 CN disclosed
US-20090238761-A1 Novel Aryl Piperazine Derivatives With Medical Utility UNIVERSITA DEGLI STUDI DI SIENA (IT) 2009-09-24 US disclosed
US-4789745-A Certain 3-[3-(3-pyridinyloxy)propoxy or propylthio]-acetic acid derivatives which are useful as synthetase inhibitors THE UPJOHN COMPANY (US) 1988-12-06 US disclosed
EP-0099685-A2 (3-Pyridinyl)heteroalkanols and alkanoic acids and esters THE UPJOHN COMPANY (US) 1984-02-01 EP disclosed
US-4192878-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1980-03-11 US disclosed