Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 4/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | OXTR | P30559 | 1/20 | 0.46 |
| ▸ | FASN | P49327 | 2/20 | 0.44 |
| ▸ | GHSR | Q92847 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3457697 | 0.92 | MAPK14 (0.57) | CNR1CNR2CA12CA1CA2 | |
| SCHEMBL3455294 | 0.86 | MAPK14 (0.63) | CNR1CNR2CA12CA1CA2 | |
| SCHEMBL22652494 | 0.73 | MAPK14 (0.57) | MAPK14OXTRCCR3 | |
| SCHEMBL23898957 | 0.73 | F11 (1.00) | F11CA12CA1CA2CA7 | |
| SCHEMBL30434722 | 0.73 | F11 (1.00) | F11CA12CA1CA2CA7 | |
| SCHEMBL1063008 | 0.71 | MAPK14 (0.69) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8161869 | 0.71 | CA12 (0.72) | F11CA12CA1CA2CA7 | |
| SCHEMBL30434910 | 0.71 | F11 (1.00) | F11CA12CA1CA2CA7 | |
| SCHEMBL23899081 | 0.71 | F11 (1.00) | F11CA12CA1CA2CA7 | |
| SCHEMBL27297526 | 0.71 | NPC1 (0.70) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009073460-A2 | INHIBITION OF 11 BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 FOR OCULAR NEUROPROTECTION | BAUSCH & LOMB INCORPORATED (US) | 2009-06-11 | — | — | WO | disclosed |