SCHEMBL4534307

SCHEMBL4534307

C=C(C)C(=O)N(N)CCC

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.36
CA12 O43570 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 1/20 0.33
TSHR P16473 3/20 0.31
MAPK1 P28482 1/20 0.31
CA1 P00915 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4805870 0.98 TDP1 (0.35) TDP1CA12CA2CA9TSHR
SCHEMBL521911 0.87 CA12 (0.38) TDP1CA12CA9TSHRCA1
SCHEMBL27617547 0.84 TSHR (0.43) TDP1TSHR
SCHEMBL28440599 0.84 TSHR (0.43) TDP1TSHR
SCHEMBL28754526 0.84 TSHR (0.43) TDP1TSHR
Ammonia Solution, Strong SCHEMBL1081945 0.84 TSHR (0.39) TDP1CA12CA2CA9TSHR
SCHEMBL4525171 0.81
SCHEMBL26658837 0.79 THRB (0.37) TSHR
SCHEMBL9809529 0.77 CA12 (0.33) CA12CA2CA9TSHRMAPK1
SCHEMBL154162 0.76 CA12 (0.46) TDP1CA12CA2CA9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12569575-B2 Radiopaque particle compositions and uses thereof GUSTAVE ROUSSY TRANSFERT (FR) 2026-03-10 US claimed
US-20240417499-A1 POLYMER PARTICLES TERUMO CORPORATION (JP) 2024-12-19 US claimed
US-12077622-B2 Polymer particles TERUMO CORPORATION (JP) 2024-09-03 US claimed
CN-117629699-A Papermaking method for improving paper strength 瑞辰星生物技术(广州)有限公司 2024-03-01 CN claimed
US-20220273825-A1 RADIOPAQUE PARTICLE COMPOSITIONS AND USES THEREOF GUSTAVE ROUSSY TRANSFERT (FR) 2022-09-01 US claimed
US-20220144990-A1 POLYMER PARTICLES TERUMO CORPORATION (JP) 2022-05-12 US claimed
US-11261274-B2 Polymer particles TERUMO CORPORATION (JP) 2022-03-01 US claimed
US-20200131287-A1 POLYMER PARTICLES MICROVENTION, INC. 2020-04-30 US claimed
US-20190031798-A1 POLYMER PARTICLES MICROVENTION, INC. 2019-01-31 US claimed
US-10118980-B1 Polymer particles TERUMO CORPORATION (JP) 2018-11-06 US claimed
US-20180298133-A1 POLYMER PARTICLES MICROVENTION, INC. 2018-10-18 US claimed
US-9688788-B2 Polymer particles TERUMO CORPORATION (JP) 2017-06-27 US claimed
EP-3065719-A1 POLYMER PARTICLES Terumo Corporation (JP) 2016-09-14 EP claimed
CN-104797671-A Highly tackified acrylate pressure sensitive adhesives 3M INNOVATIVE PROPERTIES CO 2015-07-22 CN claimed
US-20150166696-A1 POLYMER PARTICLES MICROVENTION, INC. 2015-06-18 US claimed
WO-2015070094-A1 POLYMER PARTICLES MICROVENTION, INC. (US) 2015-05-14 WO claimed
US-6126805-A A MULTICOMPARTMENT STACK COMPRISING CATION EXCHANGE MEMBRANES AND ANION EXCHANGE MEMBRANES IONICS, INCORPORATED (US) 2000-10-03 US claimed
US-12569575-B2 Radiopaque particle compositions and uses thereof GUSTAVE ROUSSY TRANSFERT (FR) 2026-03-10 US disclosed
US-4986924-A VISCOSITY INDEX, OXIDATION RESISTANCE, HEAT RESISTANCE SOCIETE NATIONALE ELF AQUITAINE (FR) 1991-01-22 US disclosed
US-4085161-A Electrodeposition of aqueous dispersions of copolymers of polyethylenically unsaturated epoxy adducts including blocked isocyanate monomer DESOTO, INC. (US) 1978-04-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12569575-B2 Radiopaque particle compositions and uses thereof PDGFRB, ERBB2, AKT1 TDP1 3973/4885CA12 3487/4885CA2 3333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.