Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL4534339

BrCCCC(Br)Cc1ccccc1.S

nearest known ligand 0.41

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.41
EPHX1 P07099 1/20 0.40
TRPA1 O75762 1/20 0.39
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
TAAR1 Q96RJ0 4/20 0.38
SIGMAR1 Q99720 3/20 0.38
SLC6A2 P23975 2/20 0.38
MAOA P21397 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38
CYP2A6 P11509 1/20 0.38
ADORA2A P29274 1/20 0.38
ADORA1 P30542 1/20 0.38
MDM2 Q00987 1/20 0.37
CYP1A2 P05177 1/20 0.36
CPA1 P15085 1/20 0.36
FOLH1 Q04609 1/20 0.36
SLC18A2 Q05940 1/20 0.35
ANPEP P15144 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6686321 0.98 TDP1 (0.43) TDP1EPHX1TRPA1ALDH1A1TSHR
SCHEMBL6689791 0.92 TDP1 (0.41) TDP1EPHX1TRPA1ALDH1A1TSHR
SCHEMBL6685311 0.90 TDP1 (0.40) TDP1EPHX1TRPA1ALDH1A1TSHR
SCHEMBL6686634 0.90 TDP1 (0.40) TDP1EPHX1TRPA1ALDH1A1TSHR
SCHEMBL6682088 0.85 TDP1 (0.46) TDP1EPHX1TRPA1ALDH1A1TSHR
Hydrogen Sulfide SCHEMBL9623454 0.80 EPHX1 (0.52) EPHX1TRPA1ALDH1A1TSHRTAAR1
SCHEMBL8746092 0.80 CSNK1E (0.47) TRPA1TAAR1SIGMAR1SLC6A2MAOA
SCHEMBL2876022 0.79 TDP1 (0.30) TDP1
SCHEMBL2581115 0.78 EPHX1 (0.39) EPHX1TSHRTAAR1SIGMAR1SLC6A2
SCHEMBL7252952 0.78 EPHX1 (0.55) TDP1EPHX1TRPA1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024041995-A1 ULTRA-LOW LOSS HYDROCARBON RESIN COMPOSITION HUNTSMAN ADVANCED MATERIALS LICENSING (SWITZERLAND) GMBH (CH) 2024-02-29 WO claimed
WO-2024041995-A1 ULTRA-LOW LOSS HYDROCARBON RESIN COMPOSITION HUNTSMAN ADVANCED MATERIALS LICENSING (SWITZERLAND) GMBH (CH) 2024-02-29 WO disclosed
US-7514379-B2 Curable polyvinyl benzyl compound and process for producing the same SHOWA HIGHPOLYMER CO., LTD. (JP) 2009-04-07 US disclosed
US-20080113176-A1 Curable polyvinyl benzyl compound and process for producing the same SHOWA HIGHPOLYMER CO., LTD. 2008-05-15 US disclosed
US-20050176909-A1 Curable polyvinyl benzyl compound and process for producing the same SHOWA HIGHPOLYMER CO., LTD. 2005-08-11 US disclosed
US-20040106758-A1 Curable polyvinylbenzyl compound and process for producing the same SHOWA HIGHPOLYMER CO., LTD. (JP) 2004-06-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040106758-A1 Curable polyvinylbenzyl compound and process for producing the same VMP1, H1-0, PBRM1 TDP1 2394/4885EPHX1 3796/4885TRPA1 1803/4885
US-20050176909-A1 Curable polyvinyl benzyl compound and process for producing the same H1-0, VMP1, PBRM1 TDP1 3174/4885EPHX1 3823/4885TRPA1 1136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.