Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28990363 | 0.93 | CSNK1E (0.37) | EPHX1TSHRMEN1KMT2ATAAR1 | |
| SCHEMBL453959 | 0.88 | EPHX1 (0.41) | EPHX1TSHRTAAR1SLC6A2SIGMAR1 | |
| SCHEMBL6686321 | 0.80 | TDP1 (0.43) | EPHX1TSHRTAAR1SLC6A2SIGMAR1 | |
| SCHEMBL6689791 | 0.78 | TDP1 (0.41) | EPHX1TSHRTAAR1SLC6A2SIGMAR1 | |
| SCHEMBL8746092 | 0.78 | CSNK1E (0.47) | TAAR1SLC6A2SIGMAR1MAOASLC6A4 | |
| Hydrogen Sulfide SCHEMBL4534339 | 0.78 | TDP1 (0.41) | EPHX1TSHRTAAR1SLC6A2SIGMAR1 | |
| SCHEMBL6685311 | 0.77 | TDP1 (0.40) | EPHX1TSHRTAAR1SLC6A2SIGMAR1 | |
| SCHEMBL6686634 | 0.77 | TDP1 (0.40) | EPHX1TSHRTAAR1SLC6A2SIGMAR1 | |
| SCHEMBL7252952 | 0.76 | EPHX1 (0.55) | EPHX1TSHRTAAR1SLC6A2SIGMAR1 | |
| SCHEMBL28523845 | 0.76 | CSNK1E (0.57) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024038866-A1 | COMPOUND, COMPOSITION, SURFACE TREATMENT AGENT, COATING LIQUID, ARTICLE, AND METHOD FOR PRODUCING ARTICLE | ＡＧＣ株式会社 | 2024-02-22 | — | — | WO | disclosed |
| EP-1796674-B1 | 5-PHENOXYALKOXYPSORALENS AND METHODS FOR SELECTIVE INHIBITION OF THE VOLTAGE GATED KV1.3 POTASSIUM CHANNEL | UNIV CALIFORNIA (US) | 2016-02-03 | — | — | EP | disclosed |
| US-8067460-B2 | 5-phenoxyalkoxypsoralens and methods for selective inhibition of the voltage gated Kv1.3 potassium channel | THE REGENTS OF THE UNIVERSITY OF CALIFONIA (US) | 2011-11-29 | — | — | US | disclosed |
| CN-101801933-A | quinolone derivative | ASTELLAS PHARMA INC | 2010-08-11 | — | — | CN | disclosed |
| US-20100121059-A1 | 5-PHENOXYALKOXYPSORALENS AND METHODS FOR SELECTIVE INHIBITION OF THE VOLTAGE GATED Kv1.3 POTASSIUM CHANNEL | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-05-13 | — | — | US | disclosed |
| US-7557138-B2 | 5-phenoxyalkoxypsoralens and methods for selective inhibition of the voltage gated Kv1.3 potassium channel | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-07-07 | — | — | US | disclosed |
| EP-1796674-A4 | 5-PHENOXYALKOXYPSORALENS AND METHODS FOR SELECTIVE INHIBITION OF THE VOLTAGE GATED KV1.3 POTASSIUM CHANNEL | UNIV CALIFORNIA (US) | 2009-07-01 | — | — | EP | disclosed |
| US-7547680-B2 | Benzimidazole derivatives and medical uses thereof | KISSEI PHARMACEUTICALS, CO., LTD. (JP) | 2009-06-16 | — | — | US | disclosed |
| US-20080038242-A1 | Benzimidazole derivatives and medical uses thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | US | disclosed |
| EP-1796674-A2 | 5-PHENOXYALKOXYPSORALENS AND METHODS FOR SELECTIVE INHIBITION OF THE VOLTAGE GATED KV1.3 POTASSIUM CHANNEL | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-06-20 | — | — | EP | disclosed |
| US-20060276444-A1 | Porphyrin-polyamine conjugates for cancer therapy | PROGEN PHARMACEUTICALS, INC. | 2006-12-07 | — | — | US | disclosed |
| WO-2006041800-A2 | 5-PHENOXYALKOXYPSORALENS AND METHODS FOR SELECTIVE INHIBITION OF THE VOLTAGE GATED KV1.3 POTASSIUM CHANNEL | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-04-20 | — | — | WO | disclosed |
| US-20060079535-A1 | 5-phenoxyalkoxypsoralens and methods for selective inhibition of the voltage gated Kv1.3 potassium channel | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-04-13 | — | — | US | disclosed |
| US-7026347-B2 | Porphyrin-polyamine conjugates for cancer therapy | CELLGATE, INC. (US) | 2006-04-11 | — | — | US | disclosed |
| EP-1515973-A1 | PORPHYRIN-POLYAMINE CONJUGATES FOR CANCER THERAPY | Cellgate Inc. (US) | 2005-03-23 | — | — | EP | disclosed |
| US-20040152687-A1 | Porphyrin-polyamine conjugates for cancer therapy | CELLGATE, INC. | 2004-08-05 | — | — | US | disclosed |
| WO-2004002991-A1 | PORPHYRIN-POLYAMINE CONJUGATES FOR CANCER THERAPY | CELLGATE, INC. (US) | 2004-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276444-A1 | Porphyrin-polyamine conjugates for cancer therapy | SRM, PAICS, FOLH1 | EPHX1 3573/4885TSHR 3082/4885MEN1 915/4885 |
| US-20080038242-A1 | Benzimidazole derivatives and medical uses thereof | SLCO1B3, SLCO2A1, SLCO2B1 | EPHX1 2367/4885TSHR 1254/4885MEN1 3420/4885 |
| US-20100121059-A1 | 5-PHENOXYALKOXYPSORALENS AND METHODS FOR SELECTIVE INHIBITION OF THE VOLTAGE GATED Kv1.3 POTASSIUM CHANNEL | KCNA3, KCNJ2, KCNQ1 | EPHX1 3223/4885TSHR 2927/4885MEN1 1600/4885 |
| US-20060079535-A1 | 5-phenoxyalkoxypsoralens and methods for selective inhibition of the voltage gated Kv1.3 potassium channel | KCNA3, KCNJ2, KCNQ1 | EPHX1 3223/4885TSHR 2927/4885MEN1 1600/4885 |
| US-20040152687-A1 | Porphyrin-polyamine conjugates for cancer therapy | SRM, PAICS, FOLH1 | EPHX1 3573/4885TSHR 3082/4885MEN1 915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.