2,6-Dichlorophenol

2,6-Dichlorophenol

SCHEMBL45346

Oc1c(Cl)cccc1Cl.Oc1ccccc1I.[Na]

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
TSHR P16473 2/20 0.46
LMNA P02545 4/20 0.39
HPGD P15428 3/20 0.39
ALOX15 P16050 3/20 0.39
TDP1 Q9NUW8 3/20 0.39
EGFR P00533 2/20 0.39
CA2 P00918 2/20 0.39
FYN P06241 2/20 0.39
MMP9 P14780 2/20 0.39
RECQL P46063 2/20 0.39
HSD17B10 Q99714 2/20 0.39
CA1 P00915 2/20 0.39
ADAMTS4 O75173 1/20 0.39
MMP2 P08253 1/20 0.39
MMP8 P22894 1/20 0.39
CA6 P23280 1/20 0.39
CDK2 P24941 1/20 0.39
MMP12 P39900 1/20 0.39
ADAMTS5 Q9UNA0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,6-Dichlorophenol SCHEMBL142668 0.98 ALDH1A1 (0.52) ALDH1A1TSHRLMNAHPGDALOX15
2-Chlorophenol SCHEMBL3835310 0.85 ALDH1A1 (0.71) ALDH1A1TSHRLMNAHPGDALOX15
SCHEMBL733271 0.83 TSHR (0.71) ALDH1A1TSHRLMNAHPGDALOX15
2,6-Dichlorophenol SCHEMBL28437484 0.82 ALDH1A1 (0.65) ALDH1A1TSHRLMNAHPGDALOX15
2,6-Dichlorophenol SCHEMBL28916675 0.80 ALDH1A1 (0.46) ALDH1A1TSHRLMNAHPGDALOX15
SCHEMBL1423760 0.80
SCHEMBL5720 0.79
2,6-Dichlorophenol SCHEMBL30257485 0.79 TSHR (0.52) ALDH1A1TSHRLMNAHPGDALOX15
SCHEMBL9564314 0.77 TSHR (0.48) ALDH1A1TSHRLMNAHPGDALOX15
Hydrogen Sulfide SCHEMBL28872365 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2450026-B1 DENTAL COMPOSITION HAVING A REDOX INDICATOR AND METHOD OF USING SAME KERR CORP (US) 2023-03-15 EP claimed
EP-2450027-B1 DENTAL COMPOSITIONS HAVING SPECIAL FUNCTIONALITY AND TRI-BARREL PACKAGING KERR CORP (US) 2023-01-11 EP claimed
US-9522099-B2 Dental compositions having special functionality and a tri-barrel packaging and delivery system therefor KERR CORPORATION (US) 2016-12-20 US claimed
US-9399004-B2 Dental composition having a redox indicator and method of using same KERR CORPORATION (US) 2016-07-26 US claimed
US-9387152-B2 Blood substitutes and uses thereof THE GENERAL HOSPITAL CORPORATION (US) 2016-07-12 US claimed
WO-2016025714-A1 CHLOROPICRIN SENSOR THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-02-18 WO claimed
US-20120115106-A1 DENTAL COMPOSITIONS HAVING SPECIAL FUNCTIONALITY AND A TRI-BARREL PACKAGING AND DELIVERY SYSTEM THEREFOR KERR CORPORATION (US) 2012-05-10 US claimed
US-20120115978-A1 DENTAL COMPOSITION HAVING A REDOX INDICATOR AND METHOD OF USING SAME KERR CORPORATION (US) 2012-05-10 US claimed
EP-2450027-A2 Dental compositions having special functionality and a tri-barrel packaging and delivery system therefor Kerr Corporation (US) 2012-05-09 EP claimed
EP-2450026-A2 Dental composition having a redox indicator and method of using same Kerr Corporation (US) 2012-05-09 EP claimed
CN-1594463-A Light catalyzed oxidation reduction degradation decolorization writing ink used for blackboard and degradation promoter thereof LIN JINDONG (CN) 2005-03-16 CN claimed
US-11993802-B2 Method for stabilizing proteins LONZA LTD (CH) 2024-05-28 US disclosed
WO-2024078778-A1 COMPOSITIONS AND METHODS FOR TREATMENT AND PREVENTION OF PATHOGENS WIAB WATER INNOVATION AB (SE) 2024-04-18 WO disclosed
US-20240122971-A1 COMPOSITIONS AND METHODS FOR TREATMENT AND PREVENTION OF PATHOGENS WIAB WATER INNOVATION AB (SE) 2024-04-18 US disclosed
CN-117500532-A Biological indicator with modulated resistance properties 3M创新有限公司 2024-02-02 CN disclosed
CN-1594463-A Light catalyzed oxidation reduction degradation decolorization writing ink used for blackboard and degradation promoter thereof LIN JINDONG (CN) 2005-03-16 CN disclosed
US-4431652-A UROGENITAL DISORDERS; KIDNEY AND BLADDER STONES; PROPHYLAXIS; OXIDASE ENZYME INHIBITORS MERCK & CO., INC. (US) 1984-02-14 US disclosed
US-4428956-A GLYCOLATE OXIDASE INHIBITORS MERCK & CO., INC. (US) 1984-01-31 US disclosed
US-4423063-A 2,4-Dioxo-4-substituted-1-butaoic acid derivatives useful in treating urinary track calcium oxalate lithiasis MERCK & CO., INC. (US) 1983-12-27 US disclosed
US-4337258-A ENZYME INHIBITOR MERCK & CO., INC. (US) 1982-06-29 US disclosed