Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.32 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.31 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Boric Acid SCHEMBL5133784 | 0.94 | ALDH1A1 (0.33) | LMNAALDH1A1 | |
| SCHEMBL73267 | 0.89 | ALDH1A1 (0.37) | LMNAFOLH1ALDH1A1 | |
| SCHEMBL686740 | 0.87 | ALDH1A1 (0.36) | LMNAALDH1A1 | |
| SCHEMBL4067005 | 0.87 | ALDH1A1 (0.36) | LMNAALDH1A1 | |
| Water SCHEMBL6002541 | 0.87 | ALDH1A1 (0.36) | LMNAALDH1A1 | |
| SCHEMBL8832202 | 0.87 | ALDH1A1 (0.36) | LMNAALDH1A1 | |
| SCHEMBL17559293 | 0.87 | ALDH1A1 (0.36) | LMNAALDH1A1 | |
| SCHEMBL15653353 | 0.87 | ALDH1A1 (0.36) | LMNAALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL6025908 | 0.87 | ALDH1A1 (0.36) | LMNAALDH1A1 | |
| SCHEMBL8718752 | 0.87 | ALDH1A1 (0.36) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541385-B2 | Bronchodilating β-agonist compositions and methods | MYLAN TECHNOLOGIES, INC. | 2009-06-02 | — | — | US | disclosed |