⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11505892 | 0.97 | — | — | |
| SCHEMBL6682754 | 0.76 | — | — | |
| SCHEMBL148339 | 0.76 | — | — | |
| SCHEMBL1018723 | 0.76 | — | — | |
| SCHEMBL450804 | 0.76 | — | — | |
| SCHEMBL181427 | 0.76 | — | — | |
| SCHEMBL6259195 | 0.76 | — | — | |
| SCHEMBL1949437 | 0.76 | — | — | |
| SCHEMBL9149843 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL2184361 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250161221-A1 | Lyophilized Pharmaceutical Compositions Comprising A Lipid Nanoparticle | TRANSLATE BIO, INC. (US) | 2025-05-22 | — | — | US | disclosed |
| US-20240408020-A1 | Lyophilized Pharmaceutical Compositions Comprising a Lipid Nanoparticle | TRANSLATE BIO, INC. (US) | 2024-12-12 | — | — | US | disclosed |
| US-12102720-B2 | Cleavable lipids | TRANSLATE BIO, INC. (US) | 2024-10-01 | — | — | US | disclosed |
| EP-3674292-B1 | CLEAVABLE LIPIDS | TRANSLATE BIO INC (US) | 2024-04-10 | — | — | EP | disclosed |
| EP-4303224-A1 | PROTEIN FOLDING AGENT | Tohoku University (JP) | 2024-01-10 | — | — | EP | disclosed |
| EP-3861001-B1 | BORON CONTAINING PDE4 INHIBITORS | PFIZER (US) | 2023-12-13 | — | — | EP | disclosed |
| EP-4212514-A1 | CLEAVABLE LIPIDS | Translate Bio, Inc. (US) | 2023-07-19 | — | — | EP | disclosed |
| US-20230148402-A1 | Boron Containing PDE4 Inhibitors | PFIZER INC. (US) | 2023-05-11 | — | — | US | disclosed |
| US-11559538-B2 | Substituted 1,2-oxaborolan-2-ols as PDE4 inhibitors | PFIZER INC. (US) | 2023-01-24 | — | — | US | disclosed |
| EP-4074693-A1 | CLEAVABLE LIPIDS | Translate Bio, Inc. (US) | 2022-10-19 | — | — | EP | disclosed |
| US-20050171132-A1 | Diaminopyrimidine derivatives as selective growth hormone secrectgogue receptor (GHS-R) antagonists | XIN ZHILI (US) | 2005-08-04 | — | — | US | disclosed |
| WO-2005030734-A1 | DIAMINOPYRIMIDINE DERIVATIVES AS SELECTIVE GROWTH HORMONE SECRECTGOGUE RECEPTOR (GHS-R) ANTAGONISTS | ABBOTT LABORATORIES (US) | 2005-04-07 | — | — | WO | disclosed |
| US-20050070712-A1 | Pyrimidine derivatives as ghrelin receptor modulators | ABBOTT LABORATORIES | 2005-03-31 | — | — | US | disclosed |
| US-6156761-A | Substituted tetralone derivatives for enhancing cognition | MERCK SHARPE & DOHME LIMITED (GB) | 2000-12-05 | — | — | US | disclosed |
| US-5314817-A | Hapten modified with pyrimidine dimer or benzylammonium group, useful in reactions of proteins, nucleic acids and carbohydrates | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-05-24 | — | — | US | disclosed |
| US-5302516-A | Polypeptides having a binding site specific for a reactant and having an active functionality near that site to promote or catalyze the reaction; kinetics | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-04-12 | — | — | US | disclosed |
| US-5215889-A | CATALYTIC AND REACTIVE POLYPEPTIDES AND METHODS FOR THEIR PREPARATION AND USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0445214-A4 | CATALYTIC AND REACTIVE POLYPEPTIDES AND METHODS FOR THEIR PREPARATION AND USE | — | 1991-11-13 | — | — | EP | disclosed |
| EP-0445214-A1 | CATALYTIC AND REACTIVE ANTIBODIES AND ANTIBODY FRAGMENTS AND METHODS FOR THEIR PREPARATION AND USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1991-09-11 | — | — | EP | disclosed |
| WO-1990005746-A1 | CATALYTIC AND REACTIVE POLYPEPTIDES AND METHODS FOR THEIR PREPARATION AND USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1990-05-31 | — | — | WO | disclosed |