SCHEMBL1018723

SCHEMBL1018723

NCc1c[nH]cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2184361 0.97
Water SCHEMBL4811962 0.97
Histamine SCHEMBL2279 0.80
Histamine SCHEMBL27340939 0.80
Histamine SCHEMBL5447892 0.80
Histamine SCHEMBL7444650 0.80 HRH4 (0.42)
Histamine SCHEMBL1668636 0.80 HRH4 (0.42)
Histamine SCHEMBL289072 0.80 HRH4 (0.42)
Histamine SCHEMBL4760179 0.78
Histamine SCHEMBL991718 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4594520-A2 COMPOSITIONS CONTAINING OLIGONUCLEOTIDES WITH THERANOSTIC APPLICATIONS Sixfold Bioscience Ltd. (GB) 2025-08-06 EP claimed
WO-2024069235-A2 COMPOSITIONS CONTAINING OLIGONUCLEOTIDES WITH THERANOSTIC APPLICATIONS Sixfold Bioscience Ltd. (GB) 2024-04-04 WO claimed
US-20230183746-A1 COMPOSITIONS FOR TRANSFER OF CARGO TO CELLS Sixfold Bioscience Ltd. (GB) 2023-06-15 US claimed
EP-4143316-A2 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY Sixfold Bioscience Ltd. (GB) 2023-03-08 EP claimed
EP-4022058-A2 COMPOSITIONS FOR TRANSFER OF CARGO TO CELLS Sixfold Bioscience Ltd. (GB) 2022-07-06 EP claimed
CN-114685572-A Oxidant composition for MGB nucleic acid probe synthesis and probe synthesis method 上海百力格生物技术有限公司 2022-07-01 CN claimed
WO-2021220053-A2 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY Sixfold Bioscience Ltd. (GB) 2021-11-04 WO claimed
EP-3807338-A1 USE OF HETEROCYCLIC AMINES CONTAINING PRIMARY OR SECONDARY AMINES AS A POLYMER CATALYST OR HARDENER Zymergen Inc. (US) 2021-04-21 EP claimed
CN-112449644-A Use of heterocyclic amines containing primary or secondary amines as polymer catalysts or hardeners 齐默尔根公司 2021-03-05 CN claimed
US-8354444-B2 Substituted pyrrolidine-2-carboxamides HOFFMANN-LA ROCHE INC. (US) 2013-01-15 US claimed
EP-2340021-B1 SUBSTITUTED PYRROLIDINE-2-CARBOXAMIDES HOFFMANN LA ROCHE (CH) 2012-11-07 EP claimed
US-20100152190-A1 Substituted Pyrrolidine-2-Carboxamides F. HOFFMANN-LA ROCHE AG (CH) 2010-06-17 US claimed
US-20100075948-A1 Substituted Pyrrolidine-2-Carboxamides DING QINGJIE 2010-03-25 US claimed
US-7683097-B2 Topoisomerase inhibitors Propharmacon Inc. (US) 2010-03-23 US claimed
CN-101185882-A High-capacity dewatering electric charge inducing color chromatogram medium and preparation method UNIV TIANJIN (CN) 2008-05-28 CN claimed
US-4662905-A REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) 1987-05-05 US claimed
US-12472267-B2 Compositions containing nucleic acid nanoparticles with modular functionality Sixfold Bioscience Ltd. (GB) 2025-11-18 US disclosed
CN-120683646-A Antibacterial knitted fabric and preparation method thereof 南通和顺兴纺织集团有限公司 2025-09-23 CN disclosed
US-4472304-A CARCINOSTATIC NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1984-09-18 US disclosed
US-4460709-A Process for producing oxygen-containing organic compounds AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) 1984-07-17 US disclosed