SCHEMBL4535386

SCHEMBL4535386

O=[N+]([O-])c1ccc(OP(=O)(O)O)c(Cl)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
HSD17B10 Q99714 1/20 0.53
PDE7A Q13946 1/20 0.52
MAPT P10636 6/20 0.49
ALDH1A1 P00352 4/20 0.49
LMNA P02545 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
KMT2A Q03164 4/20 0.48
RAB9A P51151 2/20 0.48
MEN1 O00255 2/20 0.48
GAA P10253 1/20 0.48
PKM P14618 1/20 0.48
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
NPC1 O15118 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1134003 1.00 CA1 (0.56) CA1CA2HSD17B10PDE7AMAPT
SCHEMBL28734906 0.98 CA1 (0.54) CA1CA2HSD17B10PDE7AMAPT
SCHEMBL16571907 0.88 PDE7A (0.54) CA1CA2HSD17B10PDE7AMAPT
SCHEMBL16571909 0.88 PDE7A (0.54) CA1CA2HSD17B10PDE7AMAPT
Potassium Ion SCHEMBL28734908 0.88 PDE7A (0.50) CA1CA2HSD17B10PDE7AMAPT
SCHEMBL4535383 0.87 HSD17B10 (0.56) HSD17B10PDE7AMAPTALDH1A1LMNA
SCHEMBL8565904 0.86 PDE7A (0.49) CA1CA2HSD17B10PDE7AMAPT
SCHEMBL16571905 0.85 PDE7A (0.57) HSD17B10PDE7AMAPTALDH1A1LMNA
SCHEMBL7064128 0.85 CA1 (0.61) CA1CA2ALDH1A1LMNASMN1; SMN2
SCHEMBL4823831 0.84 CA1 (0.56) CA1CA2MAPTALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4560318-A1 TRACP-5B MEASUREMENT METHOD AND KIT THEREFOR Nitto Boseki Co., Ltd. (JP) 2025-05-28 EP disclosed
CN-119630965-A Method for determining TRACP-5b and kit for use in the method 日东纺绩株式会社 2025-03-14 CN disclosed
WO-2025018136-A1 TRACP-5b MEASUREMENT METHOD AND KIT THEREFOR 日東紡績株式会社 2025-01-23 WO disclosed
US-8080375-B2 Methods and kits for detecting an enzyme capable of modifying a nucleic acid ISEAO TECHNOLOGIES LIMITED (GB) 2011-12-20 US disclosed
US-20090098539-A1 Methods and Kits for Detecting an Enzyme Capable of Modifying a Nucleic Acid ISEAO TECHNOLOGIES LIMITED (GB) 2009-04-16 US disclosed
EP-1888770-A2 IMPROVED METHODS AND KITS FOR DETECTING AN ENZYME CAPABLE OF MODIFYING A NUCLEIC ACID ISEAO Technologies Limited (GB) 2008-02-20 EP disclosed
WO-2006123154-A2 IMPROVED METHODS AND KITS FOR DETECTING AN ENZYME CAPABLE OF MODIFYING A NUCLEIC ACID ISEAO TECHNOLOGIES LIMITED (GB) 2006-11-23 WO disclosed
US-20060257879-A1 Methods and kits for detecting an enzyme capable of modifying a nucleic acid ISEAO TECHNOLOGIES LIMITED (GB) 2006-11-16 US disclosed
EP-1649059-A1 METHODS AND KITS FOR DETECTING AN ENZYME CAPABLE OF MODIFYING A NUCLEIC ACID ISEAO Technologies Limited (GB) 2006-04-26 EP disclosed
WO-2005012567-A1 METHODS AND KITS FOR DETECTING AN ENZYME CAPABLE OF MODIFYING A NUCLEIC ACID ISEAO TECHNOLOGIES LIMITED (GB) 2005-02-10 WO disclosed
US-4206280-A PHOSPHO-MONOESTER SUBSTRATE HAVING ORGANIC INDICATOR RADICAL, STRAIGHT-CHAIN ALIPHATIC ALCOHOL ACTIVATOR HOFFMANN-LA ROCHE INC. (US) 1980-06-03 US disclosed