Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1134003 | 0.86 | CA1 (0.56) | PDE7AHSD17B10CES2CES1MAPT | |
| SCHEMBL4535386 | 0.86 | CA1 (0.56) | PDE7AHSD17B10CES2CES1MAPT | |
| SCHEMBL28734906 | 0.85 | CA1 (0.54) | PDE7AHSD17B10CES2CES1MAPT | |
| SCHEMBL16571909 | 0.84 | PDE7A (0.54) | PDE7AHSD17B10CES2CES1MAPT | |
| SCHEMBL16571907 | 0.84 | PDE7A (0.54) | PDE7AHSD17B10CES2CES1MAPT | |
| Potassium Ion SCHEMBL28734908 | 0.84 | PDE7A (0.50) | PDE7AHSD17B10CES2CES1MAPT | |
| SCHEMBL4535383 | 0.83 | HSD17B10 (0.56) | PDE7AHSD17B10MAPTALDH1A1LMNA | |
| SCHEMBL16571905 | 0.81 | PDE7A (0.57) | PDE7AHSD17B10MAPTALDH1A1LMNA | |
| SCHEMBL6330127 | 0.78 | TDP1 (0.45) | MAPTLMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL1134005 | 0.76 | CES1 (0.80) | HSD17B10CES2CES1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719030-A | SUBTRACTING NON-PROSTATE DERIVED ACID PHOSPHATASE ACTIVITY MEASURED AFTER INHIBITION OF PROSTATE-DERIVED ACID PHOSPHATASE FROM MEASURED TOTAL ACID PHOSPHATASE ACTIVITY; SIMPLIFICATION | NITTO BOSEKI CO., LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0363688-B1 | Novel phosphoric acid derivatives and a method for determination of acid phosphatase activity using the same | NITTO BOSEKI CO LTD (JP) | 1994-01-05 | — | — | EP | disclosed |
| US-5227291-A | METHOD FOR DETERMINATION OF ACID PHOSPHATASE ACTIVITY USING 4-ACYL-2, 6-DIHALOPHENYL PHOSPHORIC ACID DERIVATIVES | NITTO BOSEKI CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| US-5151372-A | Measurement of UV absorbance in the presence of bilirubin or hemoglobin | NITTO BOSEKI CO., LTD. (JP) | 1992-09-29 | — | — | US | disclosed |
| US-5081274-A | Tumor diagnosis | NITTO BOSEKI CO., LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0363688-A1 | Novel phosphoric acid derivatives and a method for determination of acid phosphatase activity using the same | NITTO BOSEKI CO., LTD. (JP) | 1990-04-18 | — | — | EP | disclosed |