Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA3 | P07451 | 2/20 | 0.56 |
| ▸ | CA4 | P22748 | 2/20 | 0.56 |
| ▸ | CA6 | P23280 | 2/20 | 0.56 |
| ▸ | CA7 | P43166 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CA5A | P35218 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.47 |
| ▸ | PPARG | P37231 | 7/20 | 0.47 |
| ▸ | PPARD | Q03181 | 7/20 | 0.47 |
| ▸ | PPARA | Q07869 | 7/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Palmitic Acid SCHEMBL28715453 | 1.00 | TDP1 (0.56) | TDP1CA12CA1CA2CA3 | |
| Myristic Acid SCHEMBL28706218 | 1.00 | TDP1 (0.56) | TDP1CA12CA1CA2CA3 | |
| Oleic Acid SCHEMBL3960293 | 0.93 | EPHX2 (0.57) | TDP1LMNAALDH1A1PPARGPPARD | |
| Oleic Acid SCHEMBL3960296 | 0.93 | EPHX2 (0.57) | TDP1LMNAALDH1A1PPARGPPARD | |
| Coumarin SCHEMBL28038376 | 0.89 | CA12 (0.59) | TDP1CA12CA1CA2CA3 | |
| Arachidonic Acid SCHEMBL1128241 | 0.86 | PPARG (0.58) | TDP1LMNAALDH1A1PPARGPPARD | |
| Arachidonic Acid SCHEMBL1128240 | 0.86 | PPARG (0.58) | TDP1LMNAALDH1A1PPARGPPARD | |
| Coumarin SCHEMBL29133124 | 0.86 | CA12 (0.56) | TDP1CA12CA1CA2CA3 | |
| Hexadecanoic Acid Methyl Ester SCHEMBL31299915 | 0.85 | LMNA (0.51) | TDP1CA12CA1CA2CA3 | |
| Myristyl Alcohol SCHEMBL28340457 | 0.84 | CA12 (0.61) | TDP1CA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090011284-A1 | Core Composite Film for a Magnetic/Nonmagnetic/Magnetic Multilayer Thin Film and Its Useage | INSTITUTE OF PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) | 2009-01-08 | — | — | US | claimed |
| CN-100377868-C | Nuclear composite film for magnetic, nonmagnetic and magnetic multilayer film and use thereof | INST OF PHYSICS CAS (CN) | 2008-04-02 | — | — | CN | claimed |
| CN-1836896-A | Nuclear composite film for magnetic, nonmagnetic and magnetic multilayer film and use thereof | INST OF PHYSICS CAS (CN) | 2006-09-27 | — | — | CN | claimed |
| US-5273788-A | Preparation of diamond and diamond-like thin films | THE UNIVERSITY OF UTAH (US) | 1993-12-28 | — | — | US | claimed |
| CN-105315455-B | Preparation of glutamic acid modified polyethylene glycol monostearate and application of glutamic acid modified polyethylene glycol monostearate in targeted drug delivery | 沈阳药科大学 | 2017-10-03 | — | — | CN | disclosed |
| CN-105315455-A | Preparation of glutamic acid modified polyethylene glycol monostearate and application of glutamic acid modified polyethylene glycol monostearate in targeted drug delivery | UNIV SHENYANG PHARMACEUTICAL | 2016-02-10 | — | — | CN | disclosed |
| US-20090011284-A1 | Core Composite Film for a Magnetic/Nonmagnetic/Magnetic Multilayer Thin Film and Its Useage | INSTITUTE OF PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) | 2009-01-08 | — | — | US | disclosed |
| CN-100377868-C | Nuclear composite film for magnetic, nonmagnetic and magnetic multilayer film and use thereof | INST OF PHYSICS CAS (CN) | 2008-04-02 | — | — | CN | disclosed |
| CN-1836896-A | Nuclear composite film for magnetic, nonmagnetic and magnetic multilayer film and use thereof | INST OF PHYSICS CAS (CN) | 2006-09-27 | — | — | CN | disclosed |
| US-5273788-A | Preparation of diamond and diamond-like thin films | THE UNIVERSITY OF UTAH (US) | 1993-12-28 | — | — | US | disclosed |