SCHEMBL4535454

SCHEMBL4535454

C(=Cc1ccc(C=Cc2cccc3ccccc23)n1-c1ccccn1)c1cccc2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.49
▸ MAPK1 P28482 2/20 0.49
▸ CHAT P28329 5/20 0.42
▸ ALDH1A1 P00352 2/20 0.40
▸ CYP1A1 P04798 1/20 0.40
▸ CYP1A2 P05177 1/20 0.40
▸ CYP2D6 P10635 1/20 0.40
▸ HPGD P15428 1/20 0.40
▸ NPY1R P25929 1/20 0.40
▸ NPY2R P49146 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ CYP1B1 Q16678 1/20 0.40
▸ MTNR1A P48039 1/20 0.39
▸ MTNR1B P49286 1/20 0.39
▸ LMNA P02545 2/20 0.39
▸ KDM4E B2RXH2 2/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ RXRA P19793 1/20 0.39
▸ PTGS1 P23219 1/20 0.38
▸ PTGS2 P35354 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3162895 0.76 RAB9A (0.59) MAPTMAPK1CHATALDH1A1CYP1A1
SCHEMBL14279418 0.76 RAB9A (0.59) MAPTMAPK1CHATALDH1A1CYP1A1
SCHEMBL4157442 0.74 NPC1 (0.44) MAPTALDH1A1HPGDSMN1; SMN2LMNA
SCHEMBL4157446 0.74 NPC1 (0.44) MAPTALDH1A1HPGDSMN1; SMN2LMNA
SCHEMBL10706687 0.73 CHAT (0.62) CHATALDH1A1MTNR1AMTNR1BLMNA
SCHEMBL10706694 0.73 CHAT (0.62) CHATALDH1A1MTNR1AMTNR1BLMNA
SCHEMBL10706700 0.73 CHAT (0.62) CHATALDH1A1MTNR1AMTNR1BLMNA
SCHEMBL10437275 0.71 CHAT (0.60) CHATMTNR1AMTNR1BLMNAKDM4E
SCHEMBL10437274 0.71 CHAT (0.60) CHATMTNR1AMTNR1BLMNAKDM4E
SCHEMBL6323842 0.71 CHAT (0.51) MAPTMAPK1CHATALDH1A1CYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7531957-B2 Display apparatus and manufacturing method therefor FUJIFILM CORPORATION (JP) 2009-05-12 — — US disclosed
US-20070080627-A1 Display apparatus and manufacturing method therefor FUJI PHOTO FILM CO., LTD. (JP) 2007-04-12 — — US disclosed
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