Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 13/20 | 0.48 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.44 |
| ▸ | IL1B | P01584 | 16/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13706935 | 1.00 | P2RX7 (0.48) | P2RX7HCN4IL1B | |
| SCHEMBL13706835 | 0.96 | P2RX7 (0.47) | P2RX7HCN4IL1B | |
| SCHEMBL13706934 | 0.95 | P2RX7 (0.51) | P2RX7HCN4IL1B | |
| SCHEMBL4530444 | 0.89 | P2RX7 (0.45) | P2RX7HCN4IL1B | |
| SCHEMBL13706941 | 0.89 | P2RX7 (0.45) | P2RX7HCN4IL1B | |
| SCHEMBL4535057 | 0.88 | P2RX7 (0.50) | P2RX7HCN4IL1B | |
| SCHEMBL13706725 | 0.88 | P2RX7 (0.49) | P2RX7HCN4IL1B | |
| SCHEMBL4531278 | 0.88 | P2RX7 (0.48) | P2RX7HCN4IL1B | |
| SCHEMBL13706714 | 0.87 | P2RX7 (0.47) | P2RX7HCN4IL1B | |
| SCHEMBL13706947 | 0.87 | P2RX7 (0.47) | P2RX7HCN4IL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009108551-A2 | HETEROARYL AMIDE ANALOGUES | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | claimed |
| WO-2009108551-A2 | HETEROARYL AMIDE ANALOGUES | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | disclosed |