SCHEMBL4536097

SCHEMBL4536097

CCCCCCCCCCCCOC(=O)c1ccc2c(=O)c3cc(C)ccc3sc2c1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
NPC1 O15118 1/20 0.46
MAPT P10636 1/20 0.46
RAB9A P51151 1/20 0.46
ESR1 P03372 5/20 0.45
AKR1C4 P17516 1/20 0.43
AKR1C3 P42330 1/20 0.43
AKR1C2 P52895 1/20 0.43
AKR1C1 Q04828 1/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
STS P08842 5/20 0.41
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4543672 0.99 ALDH1A1 (0.44) ALDH1A1NPC1MAPTRAB9AESR1
SCHEMBL51151 0.96 ALDH1A1 (0.47) ALDH1A1NPC1MAPTRAB9AESR1
SCHEMBL29501106 0.96 ALDH1A1 (0.47) ALDH1A1NPC1MAPTRAB9AESR1
SCHEMBL50803 0.87 CA12 (0.44) ALDH1A1NPC1MAPTRAB9AESR1
SCHEMBL29590299 0.87 CA12 (0.44) ALDH1A1NPC1MAPTRAB9AESR1
SCHEMBL1830507 0.84 ALDH1A1 (0.43) ALDH1A1NPC1MAPTRAB9AESR1
SCHEMBL85997 0.84 ALDH1A1 (0.41) ALDH1A1NPC1MAPTRAB9AMEN1
SCHEMBL14021030 0.83 ALDH1A1 (0.37) ALDH1A1NPC1MAPTRAB9AMEN1
SCHEMBL15975540 0.82 ALDH1A1 (0.35) ALDH1A1NPC1MAPTRAB9AESR1
SCHEMBL31536332 0.82 ESR1 (0.43) ALDH1A1NPC1MAPTRAB9AESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023214010-A1 PHOTOINITIATOR PACKAGE COMPRISING SPECIALISED BISACYLPHOSPHINE OXIDE PHOTOINITIATORS AND OPTICAL BRIGHTENER SENSITIZERS IGM GROUP B. V. (NL) 2023-11-09 WO disclosed
EP-2638027-B1 LOW-EXTRACTABLE THIOXANTHONES IGM RESINS ITALIA SRL (IT) 2016-07-13 EP disclosed
EP-2638027-B1 LOW-EXTRACTABLE THIOXANTHONES IGM RESINS ITALIA SRL (IT) 2016-07-13 EP disclosed
CN-103209974-B Low-extractable thioxanthones LAMBERTI SPA 2015-04-15 CN disclosed
US-8933142-B2 Low-extractable thioxanthones LAMBERTI SPA (IT) 2015-01-13 US disclosed
US-8933142-B2 Low-extractable thioxanthones LAMBERTI SPA (IT) 2015-01-13 US disclosed
US-8933142-B2 Low-extractable thioxanthones LAMBERTI SPA (IT) 2015-01-13 US disclosed
EP-2638027-A1 LOW-EXTRACTABLE THIOXANTHONES Lamberti SpA (IT) 2013-09-18 EP disclosed
US-20130237628-A1 LOW-EXTRACTABLE THIOXANTHONES IGM RESINS ITALIA S.R.L. (IT) 2013-09-12 US disclosed
US-20130237628-A1 LOW-EXTRACTABLE THIOXANTHONES IGM RESINS ITALIA S.R.L. (IT) 2013-09-12 US disclosed
US-20130237628-A1 LOW-EXTRACTABLE THIOXANTHONES IGM RESINS ITALIA S.R.L. (IT) 2013-09-12 US disclosed
CN-103209974-A Low-extractable thioxanthones LAMBERTI SPA 2013-07-17 CN disclosed
WO-2012062692-A1 LOW-EXTRACTABLE THIOXANTHONES LAMBERTI SPA (IT) 2012-05-18 WO disclosed
WO-2012062692-A1 LOW-EXTRACTABLE THIOXANTHONES LAMBERTI SPA (IT) 2012-05-18 WO disclosed