⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8018136 | 1.00 | — | — | |
| SCHEMBL103467 | 1.00 | — | — | |
| SCHEMBL11220605 | 0.97 | TSHR (0.40) | — | |
| SCHEMBL9652371 | 0.97 | TSHR (0.40) | — | |
| SCHEMBL9652378 | 0.97 | TSHR (0.40) | — | |
| SCHEMBL16369800 | 0.91 | FAAH (0.42) | — | |
| SCHEMBL22344818 | 0.91 | FAAH (0.42) | — | |
| SCHEMBL22553028 | 0.91 | TRPV1 (0.38) | — | |
| SCHEMBL22553027 | 0.91 | TRPV1 (0.38) | — | |
| SCHEMBL19973785 | 0.91 | TRPV1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2472 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4385505-A1 | ANTI-HYPOXIC/ANOXIC INJURY USE OF MAGNOLOL AND/OR HONOKIOL AROMATIC RING AMINO-SUBSTITUTED DERIVATIVE, AND PHARMACEUTICAL COMPOSITION | Beijing Honghui Meditech Co., Ltd. (CN) | 2024-06-19 | — | — | EP | claimed |
| CN-117983302-A | Catalyst containing ferrocene PNP ligand for ethylene selective tetramerization and preparation method and application thereof | 华东理工大学 | 2024-05-07 | — | — | CN | claimed |
| US-20240002450-A1 | ANTIVIRAL STRUCTURALLY-STABILIZED EBOLAVIRUS PEPTIDES AND USES THEREOF | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2024-01-04 | — | — | US | claimed |
| US-20230339840-A1 | Preparation method for water-soluble magnolol derivatives and honokiol derivatives and intermediates thereof, and related monohydroxy protection intermediates | BEIJING HONGHUI MEDITECH CO., LTD (CN) | 2023-10-26 | — | — | US | claimed |
| EP-4240395-A1 | ANTIVIRAL STRUCTURALLY-STABILIZED EBOLAVIRUS PEPTIDES AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2023-09-13 | — | — | EP | claimed |
| EP-4212509-A1 | METHOD FOR PREPARING WATER-SOLUBLE MAGNOLOL DERIVATIVE AND HONOKIOL DERIVATIVE, METHODS FOR PREPARING INTERMEDIATES OF WATER-SOLUBLE MAGNOLOL DERIVATIVE AND HONOKIOL DERIVATIVE, AND RELATED MONOHYDROXY PROTECTED INTERMEDIATE | Beijing Honghui Meditech Co., Ltd (CN) | 2023-07-19 | — | — | EP | claimed |
| WO-2023088062-A1 | ANTI-HYPOXIC/ANOXIC INJURY USE OF MAGNOLOL AND/OR HONOKIOL AROMATIC RING AMINO-SUBSTITUTED DERIVATIVE, AND PHARMACEUTICAL COMPOSITION | 北京红惠新医药科技有限公司 | 2023-05-25 | — | — | WO | claimed |
| CN-116139115-A | Application of magnolol and/or honokiol aromatic ring amino substituted derivatives in resisting hypoxia/anoxia injury and pharmaceutical composition | 北京红惠新医药科技有限公司 | 2023-05-23 | — | — | CN | claimed |
| WO-2022098848-A1 | ANTIVIRAL STRUCTURALLY-STABILIZED EBOLAVIRUS PEPTIDES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-05-12 | — | — | WO | claimed |
| WO-2014144547-A2 | AMIDE DERIVATIVES OF LACTAM BASED N-ACYLETHANOLAMINE ACID AMIDASE (NAAA) INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-09-18 | — | — | WO | claimed |
| US-5371076-A | ANTIBIOTICS | AMERICAN CYANAMID COMPANY (US) | 1994-12-06 | — | — | US | claimed |
| EP-0618190-A1 | 9-[(Substituted glycyl)amido]-6-(substituted)-5-hydroxy-6-deoxytetracyclines | AMERICAN CYANAMID COMPANY (US) | 1994-10-05 | — | — | EP | claimed |
| US-5328902-A | Antibiotics | AMERICAN CYANAMID CO. (US) | 1994-07-12 | — | — | US | claimed |
| EP-0582789-A1 | Novel 7-(substituted)-8-(substituted)-9- (substituted glycyl)amido -6-demethyl-6-deoxytetracyclines | AMERICAN CYANAMID COMPANY (US) | 1994-02-16 | — | — | EP | claimed |
| EP-0582788-A1 | 7-(Substituted)-9- (substituted glycyl)-amido)-6-demethyl-6-deoxytetracyclines | AMERICAN CYANAMID COMPANY (US) | 1994-02-16 | — | — | EP | claimed |
| EP-0582829-A1 | 9-(substituted glycyl) amido - 6-demethyl-6-deoxytetracyclines as antibiotic agents | AMERICAN CYANAMID COMPANY (US) | 1994-02-16 | — | — | EP | claimed |
| US-5190689-A | Polymer materials having liquid-crystalline phases | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-03-02 | — | — | US | claimed |
| EP-0234348-B1 | N-GLYCOSYL AMIDE DERIVATIVES, METHOD FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | BAYER AG (DE) | 1991-05-29 | — | — | EP | claimed |
| US-4891425-A | IMMUNOSTIMULANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-01-02 | — | — | US | claimed |
| EP-0234348-A2 | N-glycosyl amide derivatives, method for their preparation and their use as medicaments | BAYER AG (DE) | 1987-09-02 | — | — | EP | claimed |