⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL11276850 | 0.82 | NAPRT (0.56) | — | |
| SCHEMBL28906689 | 0.82 | — | — | |
| SCHEMBL28516487 | 0.82 | — | — | |
| SCHEMBL305319 | 0.82 | ALDH1A1 (0.49) | — | |
| SCHEMBL29852296 | 0.82 | ALDH1A1 (0.49) | — | |
| SCHEMBL7999163 | 0.79 | ALDH1A1 (0.46) | — | |
| SCHEMBL17799 | 0.78 | — | — | |
| SCHEMBL17201196 | 0.78 | — | — | |
| SCHEMBL3085028 | 0.77 | GAA (0.55) | — | |
| SCHEMBL12975502 | 0.77 | NAPRT (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 776 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115851090-A | Antibacterial water-based paint spraying coating and processing technology thereof | 厦门市金宝源实业有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-110612119-A | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents | 西雅图儿童医院（DBA西雅图儿童研究所） | 2019-12-24 | — | — | CN | claimed |
| WO-2018148224-A1 | PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS | Seattle Children's Hospital (dba Seattle Children's Research Institute) (US) | 2018-08-16 | — | — | WO | claimed |
| US-8907096-B2 | N-adamantyl benzamides as inhibitors of 11-β-hydroxysteroid dehydrogenase | HIGH POINT PHARMACEUTICALS, LLC (US) | 2014-12-09 | — | — | US | claimed |
| US-20140315905-A1 | N-ADAMANTYL BENZAMIDES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE | VTV THERAPEUTICS LLC | 2014-10-23 | — | — | US | claimed |
| US-8809540-B2 | N-adamantyl benzamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase | HIGH POINT PHARMACEUTICALS, LLC (US) | 2014-08-19 | — | — | US | claimed |
| US-20130231341-A1 | N-ADAMANTYL BENZAMIDES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE | HIGH POINT PHARMACEUTICALS, LLC (US) | 2013-09-05 | — | — | US | claimed |
| US-8383820-B2 | N-adamantyl benzamides as inhibitors of 11-β-hydroxysteroid dehydrogenase | HIGH POINT PHARMACEUTICALS, LLC (US) | 2013-02-26 | — | — | US | claimed |
| JP-2011524881-A | — | — | 2011-09-08 | — | — | JP | claimed |
| EP-2307385-A1 | 2 -ARYLAMINOQUINAZOLINES FOR TREATING PROLIFERATIVE DISEASES | Novartis AG (CH) | 2011-04-13 | — | — | EP | claimed |
| US-7919627-B2 | Synthesis of O-(6-pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine derivatives by protecting the hydroxyl group of (6-chloro-pyridin-3-yl)-methanol, reacting with pyrazole, and reacting with hydroxylamine or a derivative or an oxime | ENANTA PHARMACEUTICALS, INC. (US) | 2011-04-05 | — | — | US | claimed |
| US-20100121052-A1 | Novel compounds for treating proliferative diseases | JAIN RAMA | 2010-05-13 | — | — | US | claimed |
| WO-2009153313-A1 | 2 -ARYLAMINOQUINAZOLINES FOR TREATING PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 2009-12-23 | — | — | WO | claimed |
| US-20080242865-A1 | PROCESSES FOR THE PREPARATION OF HYDROXYLAMINES | TANG DATONG | 2008-10-02 | — | — | US | claimed |
| WO-2006119417-A1 | PROCESSES FOR THE PREPARATION OF O-(6-PYRAZOL-1-YL-PYRIDIN-3-YLMETHYL)-HYDROXYLAMINE | ENANTA PHARMACEUTICALS, INC. (US) | 2006-11-09 | — | — | WO | claimed |
| US-20060247440-A1 | Processes for the preparation of O-(6-pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine | ENANTA PHARMACEUTICALS, INC. | 2006-11-02 | — | — | US | claimed |
| JP-6315390-A | — | — | None | — | — | JP | disclosed |
| JP-9056376-A | — | — | None | — | — | JP | disclosed |
| US-4332944-A | Compositions and use | ZOECON CORPORATION (US) | 1982-06-01 | — | — | US | disclosed |
| JP-H00956376-A | — | — | 0001-01-01 | — | — | JP | disclosed |