SCHEMBL4537689

SCHEMBL4537689

Nc1cccc(-c2cccc(N)c2S(=O)(=O)O)c1S(=O)(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.48
DAPK1 P53355 1/20 0.44
ALDH1A1 P00352 6/20 0.42
TSHR P16473 5/20 0.42
HSD17B10 Q99714 4/20 0.42
TDP1 Q9NUW8 3/20 0.42
ADORA2A P29274 2/20 0.42
PTPRC P08575 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.40
NT5E P21589 1/20 0.38
GAA P10253 1/20 0.38
AURKA O14965 1/20 0.38
AURKB Q96GD4 1/20 0.38
CSNK1A1 P48729 2/20 0.37
CSNK1D P48730 2/20 0.37
CSNK1G1 Q9HCP0 2/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CYP2C9 P11712 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28255760 0.89 TTR (0.53) TTRDAPK1ALDH1A1TSHRHSD17B10
SCHEMBL668652 0.88 TTR (0.54) TTRDAPK1ALDH1A1TSHRHSD17B10
SCHEMBL11430380 0.86 TTR (0.52) TTRDAPK1ALDH1A1TSHRHSD17B10
SCHEMBL28407130 0.86 TTR (0.52) TTRDAPK1ALDH1A1TSHRHSD17B10
SCHEMBL2006103 0.82 TTR (0.64) TTRDAPK1ALDH1A1TSHRHSD17B10
SCHEMBL6412687 0.82 ALDH1A1 (0.49) TTRDAPK1ALDH1A1TSHRHSD17B10
SCHEMBL6530986 0.81 TTR (0.53) TTRDAPK1ALDH1A1TSHRHSD17B10
SCHEMBL27406090 0.80 ALDH1A1 (0.42) TTRDAPK1ALDH1A1TSHRHSD17B10
SCHEMBL15194288 0.80 TTR (0.62) TTRDAPK1ALDH1A1TSHRHSD17B10
SCHEMBL1755214 0.80 AURKA (0.49) TTRDAPK1ALDH1A1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117642224-A Method for producing hollow fiber carbon film 陶氏环球技术有限责任公司 2024-03-01 CN claimed
CN-115842129-A Polyimide for lithium battery silicon-based negative electrode binder and silicon-based negative electrode 浙江中科玖源新材料有限公司 2023-03-24 CN claimed
CN-117946355-B Preparation method and application of asymmetric self-supporting covalent organic framework film 中国科学技术大学 2024-06-18 CN disclosed
CN-118001941-A Composite nanofiltration membrane for magnesium-lithium separation and preparation method and application thereof 江南大学 2024-05-10 CN disclosed
CN-117946355-A Preparation method and application of asymmetric self-supporting covalent organic framework film 中国科学技术大学 2024-04-30 CN disclosed
CN-114026150-B Polyamide-imide resin, resin composition, and semiconductor device 株式会社力森诺科 2024-04-05 CN disclosed
CN-117642224-A Method for producing hollow fiber carbon film 陶氏环球技术有限责任公司 2024-03-01 CN disclosed
CN-117018866-A Nanofiltration membrane for screening low molecular weight organic matters and preparation method thereof 北京工业大学 2023-11-10 CN disclosed
CN-116940618-A Polyamide-imide resin, resin composition, and semiconductor device 株式会社力森诺科 2023-10-24 CN disclosed
CN-112574411-B Polyimide precursor, polyimide film, preparation method of polyimide film and display device 武汉柔显科技股份有限公司 2023-06-02 CN disclosed
CN-116144022-A Polyimide polymer, polyimide film, preparation method and application 中国科学院山西煤炭化学研究所 2023-05-23 CN disclosed
US-20010020082-A1 Sulphonated polyimides, membranes prepared with them, and a fuel cell device that includes these membranes FAURE SYLVAIN (FR) 2001-09-06 US disclosed
US-6245881-B1 SULFONATED AROMATIC POLYIMIDES; DURABLE ION EXCHANGE MEMBRANES SUITABLE FOR FUEL CELLS IN ELECTRIC VEHICLES COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2001-06-12 US disclosed
EP-0738261-A1 PHARMACEUTICAL FORMULATIONS COMPRISING POLYTHIOUREA AND METHOD OF USE THEREOF MERRELL DOW PHARMACEUTICALS INC. (US) 1996-10-23 EP disclosed
WO-1995018791-A1 PHARMACEUTICAL FORMULATIONS COMPRISING POLYTHIOUREA AND METHOD OF USE THEREOF MERRELL DOW PHARMACEUTICALS INC. (US) 1995-07-13 WO disclosed
EP-0394505-A1 Crosslinkable, sulfonated, aromatic polyamides and polyureas THE DOW CHEMICAL COMPANY (US) 1990-10-31 EP disclosed
EP-0356931-A2 Anthrapyridone compounds having vinylsulfone type fiber reactive group through triazinyl bridging group SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-03-07 EP disclosed
EP-0176857-B1 PIGMENT COMPOSITIONS BASF Lacke + Farben AG (DE) 1989-07-19 EP disclosed
US-4720304-A Pigment formulations BASF FARBEN+FASERN AKTIENGESELLSCHAFT (DE) 1988-01-19 US disclosed
EP-0176857-A2 Pigment compositions BASF Lacke + Farben AG (DE) 1986-04-09 EP disclosed