Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.84 |
| ▸ | PGR | P06401 | 5/20 | 0.84 |
| ▸ | LMNA | P02545 | 3/20 | 0.81 |
| ▸ | NR3C1 | P04150 | 9/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.76 |
| ▸ | AR | P10275 | 2/20 | 0.76 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.76 |
| ▸ | TNF | P01375 | 1/20 | 0.76 |
| ▸ | IL6 | P05231 | 1/20 | 0.76 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.76 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.76 |
| ▸ | GLUL | P15104 | 1/20 | 0.76 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.76 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.76 |
| ▸ | USP2 | O75604 | 1/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14867443 | 0.94 | HIF1A (0.85) | HIF1APGRLMNANR3C1CYP3A4 | |
| SCHEMBL16009510 | 0.94 | HIF1A (0.91) | HIF1APGRLMNANR3C1CYP3A4 | |
| SCHEMBL11068483 | 0.93 | HIF1A (0.84) | HIF1APGRLMNANR3C1CYP3A4 | |
| SCHEMBL10363483 | 0.93 | HIF1A (0.82) | HIF1APGRLMNANR3C1CYP3A4 | |
| SCHEMBL10988088 | 0.93 | HIF1A (0.80) | HIF1APGRLMNANR3C1CYP3A4 | |
| SCHEMBL10988077 | 0.93 | HIF1A (0.80) | HIF1APGRLMNANR3C1CYP3A4 | |
| SCHEMBL677625 | 0.93 | HIF1A (0.82) | HIF1APGRLMNANR3C1CYP3A4 | |
| SCHEMBL2320418 | 0.92 | HIF1A (0.82) | HIF1APGRLMNANR3C1CYP3A4 | |
| SCHEMBL11043702 | 0.92 | HIF1A (0.82) | HIF1APGRLMNANR3C1CYP3A4 | |
| SCHEMBL11043699 | 0.92 | HIF1A (0.82) | HIF1APGRLMNANR3C1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117599290-A | Pressurized metered dose inhaler comprising buffered pharmaceutical formulation | 奇斯药制品公司 | 2024-02-27 | — | — | CN | claimed |
| CN-116098866-A | Glucocorticoid fat emulsion for treating arthralgia, preparation method and application thereof | 中南大学湘雅医院 | 2023-05-12 | — | — | CN | claimed |
| US-4478818-A | Ocular preparation housing steroid in two different therapeutic forms | ALZA CORPORATION (US) | 1984-10-23 | — | — | US | claimed |
| CN-111902146-B | Medicinal products for treating cough | 日本化学药品株式会社 | 2024-04-12 | — | — | CN | disclosed |
| CN-117599290-A | Pressurized metered dose inhaler comprising buffered pharmaceutical formulation | 奇斯药制品公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-117320699-A | Vesicle and application thereof | 埃克索丘尔瑞典公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-114126574-B | External preparation for skin | 花王株式会社 | 2023-11-21 | — | — | CN | disclosed |
| CN-116437928-A | Pharmaceutical composition for preventing, inhibiting or treating symptoms associated with allergic reactions | 日本化学药品株式会社 | 2023-07-14 | — | — | CN | disclosed |
| CN-116419749-A | Pharmaceutical formulation for pressurized metered-dose inhalers | 奇斯药制品公司 | 2023-07-11 | — | — | CN | disclosed |
| CN-110339346-B | External skin preparation composition | IGISU株式会社 | 2023-06-27 | — | — | CN | disclosed |
| CN-111465404-B | Wild buckwheat rhizome nutrient pharmaceutical composition | DST制药公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-114929246-A | Use of iodide compounds for the treatment and prevention of chemotherapy-associated cachexia and cardiotoxicity | 法拉第制药公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-114466658-A | Orally delivered therapeutic compositions and uses thereof | 沈海发 | 2022-05-10 | — | — | CN | disclosed |
| CN-113710255-A | Treatment of heart failure | 儿童医学中心公司 | 2021-11-26 | — | — | CN | disclosed |
| CN-112321579-A | Salts of 2-amino-1-hydroxyethyl-8-hydroxyquinolin-2 (1H) -one derivatives | 阿尔米雷尔有限公司 | 2021-02-05 | — | — | CN | disclosed |
| CN-111683653-A | Methods and compositions for topical delivery | 伊拉斯吹斯制药有限公司 | 2020-09-18 | — | — | CN | disclosed |
| WO-2009020601-A2 | ATF4 INHIBITORS AND THEIR USE FOR NEURAL PROTECTION, REPAIR, REGENERATION, AND PLASTICITY | CORNELL UNIVERSITY (US) | 2009-02-12 | — | — | WO | disclosed |
| US-4478818-A | Ocular preparation housing steroid in two different therapeutic forms | ALZA CORPORATION (US) | 1984-10-23 | — | — | US | disclosed |
| US-4432964-A | Topical composition containing steroid in two forms released independently from polymeric carrier | ALZA CORPORATION (US) | 1984-02-21 | — | — | US | disclosed |
| US-4304765-A | Ocular insert housing steroid in two different therapeutic forms | ALZA CORPORATION (US) | 1981-12-08 | — | — | US | disclosed |