SCHEMBL677625

SCHEMBL677625

CCCCC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3C(O)C[C@@]21C

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.82
LMNA P02545 2/20 0.82
PGR P06401 4/20 0.80
NR3C1 P04150 8/20 0.72
CYP3A4 P08684 3/20 0.72
HSD17B10 Q99714 2/20 0.72
AR P10275 2/20 0.72
ABCB11 O95342 1/20 0.72
TNF P01375 1/20 0.72
IL6 P05231 1/20 0.72
SERPINA6 P08185 1/20 0.72
NR3C2 P08235 1/20 0.72
GLUL P15104 1/20 0.72
ADAM17 P78536 1/20 0.72
GPBAR1 Q8TDU6 1/20 0.72
CYP2C19 P33261 1/20 0.72
SMN1; SMN2 Q16637 2/20 0.70
POLB P06746 1/20 0.70
GAA P10253 1/20 0.70
MAPT P10636 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10363483 1.00 HIF1A (0.82) HIF1ALMNAPGRNR3C1CYP3A4
SCHEMBL7985 0.98 HIF1A (0.80) HIF1ALMNAPGRNR3C1CYP3A4
SCHEMBL7142738 0.98 HIF1A (0.79) HIF1ALMNAPGRNR3C1CYP3A4
SCHEMBL7613021 0.98 HIF1A (0.79) HIF1ALMNAPGRNR3C1CYP3A4
SCHEMBL7145316 0.98 HIF1A (0.79) HIF1ALMNAPGRNR3C1CYP3A4
SCHEMBL11090884 0.98 HIF1A (0.79) HIF1ALMNAPGRNR3C1CYP3A4
Prednisolone Acetate SCHEMBL9838659 0.97 HIF1A (0.86) HIF1ALMNAPGRNR3C1CYP3A4
SCHEMBL16018292 0.97 HIF1A (0.85) HIF1ALMNAPGRNR3C1CYP3A4
Prednisolone Steaglate SCHEMBL136864 0.96 HIF1A (0.77) HIF1ALMNAPGRNR3C1CYP3A4
SCHEMBL11068483 0.96 HIF1A (0.84) HIF1ALMNAPGRNR3C1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 355 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120154586-A Powder aerosol composition for inhalation, powder aerosol for inhalation, preparation method of powder aerosol for inhalation and powder aerosol for inhalation 上海臣邦医药科技股份有限公司 2025-06-17 CN claimed
CN-118662643-A Application of hormone medicine composition in preparation of medicine for treating osteoarthritis 中南大学湘雅医院 2024-09-20 CN claimed
CN-116940197-A Light emitting diode and preparation method thereof TCL科技集团股份有限公司 2023-10-24 CN claimed
CN-116098866-A Glucocorticoid fat emulsion for treating arthralgia, preparation method and application thereof 中南大学湘雅医院 2023-05-12 CN claimed
CN-116077465-A Nanometer preparation for joint pain relief, and preparation method and application thereof 中南大学湘雅医院 2023-05-09 CN claimed
CN-116077669-A Glucocorticoid nano-lipid carrier for treating arthralgia, preparation method and application thereof 中南大学湘雅医院 2023-05-09 CN claimed
CN-114698370-A Compounds and methods for treating cytokine release syndrome 里格尔药品股份有限公司 2022-07-01 CN claimed
CN-114685591-A Refining method and application of C1, 2-position dehydrosteroid compound 天津药业研究院股份有限公司 2022-07-01 CN claimed
WO-2022089499-A1 PREFERRED METHOD OF USING LEVALBUTEROL SULFATE FOR THE TREATMENT OF RESPIRATORY DISEASES 苏州君宁新药开发中心有限公司 2022-05-05 WO claimed
CN-114286679-A Methods of blocking or ameliorating cytokine release syndrome 里格尔药品股份有限公司 2022-04-05 CN claimed
CN-101060831-A Conveniently implantable sustained release pharmaceutical composition RAMSCOR INC (US) 2007-10-24 CN claimed
CN-1267087-C Pharmaceutical tablet PHARMACIA CORP (US) 2006-08-02 CN claimed
CN-1761487-A Dispersible formulations of anti-inflammatory agents PHARMACIA CORP (US) 2006-04-19 CN claimed
CN-1761486-A Dispersible pharmaceutical composition for treating mastitis and otic disorders PHARMACIA CORP (US) 2006-04-19 CN claimed
CN-1630512-A Pharmaceutical tablet PHARMACIA CORP (US) 2005-06-22 CN claimed
CN-1627938-A Pharmaceutical dosage form for transmucosal delivery PHARMACIA CORP (US) 2005-06-15 CN claimed
CN-1433396-A Pharmaceutical compounds NICOX SA (FR) 2003-07-30 CN claimed
CN-1420891-A Pharmaceutical compounds NICOX SA (FR) 2003-05-28 CN claimed
US-4765983-A INTESTINAL-SOLUBLE POLYMER AND MEDICAMENT YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1988-08-23 US claimed
US-4478818-A Ocular preparation housing steroid in two different therapeutic forms ALZA CORPORATION (US) 1984-10-23 US claimed