SCHEMBL45384

SCHEMBL45384

C[CH]NC(C)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1956799 0.74 KDM4E (0.44)
SCHEMBL8880726 0.74
SCHEMBL4856818 0.74 KDM4E (0.44)
SCHEMBL4856814 0.74 KDM4E (0.44)
SCHEMBL1358143 0.73
SCHEMBL1358140 0.73
SCHEMBL6194847 0.73
SCHEMBL3667831 0.71
SCHEMBL87987 0.71
SCHEMBL7607430 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2414 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4393909-A1 HYDANTOIN COMPOUND AND MEDICAL USE THEREOF Harbin Medisan Pharmaceutical Co., LTD. (CN) 2024-07-03 EP claimed
EP-4378931-A1 TRIAZOLONE COMPOUND AND MEDICINAL USE THEREOF Harbin Medisan Pharmaceutical Co., LTD. (CN) 2024-06-05 EP claimed
EP-4373825-A1 NITRILE SUMO INHIBITORS AND USES THEREOF Suvalent Therapeutics, Inc. (US) 2024-05-29 EP claimed
EP-4373835-A1 MACROCYLIC IMMUNOMODULATORS Bristol-Myers Squibb Company (US) 2024-05-29 EP claimed
WO-2023225661-A1 MACROCYCLIC IMMUNOMODULATORS BRISTOL-MYERS SQUIBB COMPANY (US) 2023-11-23 WO claimed
US-20230303584-A1 4,5,6,7-TETRAHYDROTHIENO[2,3-C]PYRIDINE SUMO INHIBITORS AND USES THEREOF CIT THERAPEUTICS LLC 2023-09-28 US claimed
EP-3388433-B1 PHTHALAZINE DERIVATIVES, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF SHANGHAI SIMR BIOTECH CO LTD (CN) 2023-08-30 EP claimed
WO-2023138302-A1 HYDANTOIN COMPOUND AND MEDICAL USE THEREOF 哈尔滨三联药业股份有限公司 2023-07-27 WO claimed
EP-3632443-B1 ANTI-TUMOR EFFECT POTENTIATOR USING A BIPHENYL COMPOUND TAIHO PHARMACEUTICAL CO LTD (JP) 2023-06-07 EP claimed
CN-115894379-A Hydantoin compound and medical application thereof 中国药科大学 2023-04-04 CN claimed
WO-1984000547-A1 FLUORALKYLATEDCARBAPENEM DERIVATIVES SANDOZ AG (AT) 1984-02-16 WO claimed
EP-0060612-A1 Process for the preparation of azabicyclo(3.2.0)-hept-2-ene derivatives BEECHAM GROUP PLC (GB) 1982-09-22 EP claimed
US-4337061-A NITRO DYES IN AQUEOUS SOLUTION SOCIETE ANONYME DITE: L'OREAL (FR) 1982-06-29 US claimed
US-4315855-A Monoazo disperse dyes containing a nitrophenyl group and a homophthalimide group BASF AKTIENGESELLSCHAFT (DE) 1982-02-16 US claimed
US-4311478-A HAIR DYES L'OREAL (FR) 1982-01-19 US claimed
EP-0041768-A2 Beta-lactam compounds, their preparation and use BEECHAM GROUP PLC (GB) 1981-12-16 EP claimed
US-4200432-A HAIR DYES L'OREAL (FR) 1980-04-29 US claimed
US-4123607-A BACTERICIDES AMERICAN CYANAMID COMPANY (US) 1978-10-31 US claimed
US-3998801-A MONOAZO DYES; POLYAMIDES; RED TO VIOLET SHADES EASTMAN KODAK COMPANY (US) 1976-12-21 US claimed
US-3957766-A BACTERIOSTATS, BACTERICIDES BOEHRINGER MANNHEIM G.M.B.H. (DT) 1976-05-18 US claimed