Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4540046 | 0.85 | MAPT (0.43) | MAPTNPSR1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4539989 | 0.85 | MAPT (0.43) | MAPTNPSR1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4540145 | 0.85 | CYP1A2 (0.49) | MAPTNPSR1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4540292 | 0.82 | MAPT (0.64) | MAPTNPSR1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4542687 | 0.81 | MAPT (0.45) | MAPTNPSR1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21903236 | 0.77 | MAPT (0.40) | MAPTNPSR1CYP3A4KMT2AOPRK1 | |
| Acetonitrile SCHEMBL27922454 | 0.74 | BDKRB1 (0.40) | MAPTMEN1PPARGKMT2ANR2E3 | |
| SCHEMBL4541749 | 0.74 | MAPT (0.47) | MAPTNPSR1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27857191 | 0.73 | KMT2A (0.43) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4542793 | 0.72 | BDKRB1 (0.44) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |