Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1423444 | 0.75 | — | — | |
| SCHEMBL2914663 | 0.67 | TSHR (0.31) | — | |
| SCHEMBL28139809 | 0.63 | — | — | |
| SCHEMBL28139186 | 0.59 | — | — | |
| SCHEMBL8866126 | 0.59 | — | — | |
| SCHEMBL4540593 | 0.56 | — | — | |
| SCHEMBL6952571 | 0.56 | GAA (0.30) | — | |
| SCHEMBL28428311 | 0.55 | CHRM2 (0.39) | MEN1KMT2A | |
| SCHEMBL8866002 | 0.55 | — | — | |
| SCHEMBL30121408 | 0.54 | CHRM2 (0.34) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009153179-A1 | PYRROLIDINE DERIVATIVES AS NK2 RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-12-23 | — | — | WO | disclosed |