Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL10511294 | 0.97 | TSHR (0.37) | TSHRALDH1A1FAAHSMN1; SMN2MAPT | |
| SCHEMBL22105 | 0.83 | — | — | |
| SCHEMBL27922143 | 0.83 | TSHR (0.38) | TSHRALDH1A1SMN1; SMN2MAPTKMT2A | |
| Butane SCHEMBL4909113 | 0.81 | TSHR (0.40) | TSHRALDH1A1FAAH | |
| Ethylene Glycol SCHEMBL27841984 | 0.81 | TSHR (0.39) | TSHRALDH1A1SMN1; SMN2MAPTKMT2A | |
| Ethyl Chloride SCHEMBL6536541 | 0.81 | TSHR (0.33) | TSHRALDH1A1FAAH | |
| Diethylamine SCHEMBL27842865 | 0.81 | TP53 (0.50) | TSHRALDH1A1FAAHKMT2A | |
| Ethylamine SCHEMBL1685449 | 0.81 | ALDH1A1 (0.39) | TSHRALDH1A1FAAH | |
| Dimethylamine SCHEMBL5156968 | 0.80 | TSHR (0.33) | TSHRALDH1A1SMN1; SMN2MAPT | |
| Hypochlorous Acid SCHEMBL11208004 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1777239-B1 | Half-metallocene catalyst and process for preparing syndiotactic styrene polymer using the same | LG CHEMICAL LTD (KR) | 2014-09-10 | — | — | EP | disclosed |
| US-7592404-B2 | Half metallocene catalyst and process for preparing syndiotactic styren polymer using the same | LG CHEM, LTD. (KR) | 2009-09-22 | — | — | US | disclosed |
| US-20070105710-A1 | Half metallocene catalyst and process for preparing syndiotactic styren polymer using the same | LG CHEM, LTD. (KR) | 2007-05-10 | — | — | US | disclosed |
| EP-1777239-A1 | Half-metallocene catalyst and process for preparing syndiotactic styrene polymer using the same | LG Chem Ltd. (KR) | 2007-04-25 | — | — | EP | disclosed |