SCHEMBL4540119

SCHEMBL4540119

CCCCCCCCCCCCCCCCCCNCC(O)(O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.55
ALDH1A1 P00352 1/20 0.55
S1PR2 O95136 5/20 0.45
S1PR4 O95977 5/20 0.45
S1PR1 P21453 5/20 0.45
S1PR3 Q99500 5/20 0.45
S1PR5 Q9H228 1/20 0.45
EPHX1 P07099 8/20 0.44
ADH1B P00325 1/20 0.44
ADH1C P00326 1/20 0.44
ADH1A P07327 1/20 0.44
ADH4 P08319 1/20 0.44
ADH7 P40394 1/20 0.44
GNAI3 P08754 1/20 0.44
GNAO1 P09471 1/20 0.44
GNAI1 P63096 1/20 0.44
POLB P06746 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ANPEP P15144 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8871137 1.00 TSHR (0.55) TSHRALDH1A1S1PR2S1PR4S1PR1
SCHEMBL15309934 1.00 TSHR (0.55) TSHRALDH1A1S1PR2S1PR4S1PR1
SCHEMBL8871452 1.00 TSHR (0.55) TSHRALDH1A1S1PR2S1PR4S1PR1
SCHEMBL9575912 1.00 TSHR (0.55) TSHRALDH1A1S1PR2S1PR4S1PR1
SCHEMBL8871024 1.00 TSHR (0.55) TSHRALDH1A1S1PR2S1PR4S1PR1
SCHEMBL3284743 1.00 TSHR (0.55) TSHRALDH1A1S1PR2S1PR4S1PR1
SCHEMBL4538493 1.00 TSHR (0.55) TSHRALDH1A1S1PR2S1PR4S1PR1
Bromide SCHEMBL9575940 0.98 TSHR (0.52) TSHRALDH1A1S1PR2S1PR4S1PR1
Hydrochloric Acid SCHEMBL2060000 0.98 ALDH1A1 (0.52) TSHRALDH1A1S1PR2S1PR4S1PR1
Water SCHEMBL11079491 0.98 TSHR (0.52) TSHRALDH1A1S1PR2S1PR4S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012064703-A1 DOPO-DERIVED FLAME RETARDANT AND SYNTHETIC HYDROGARNETS FOR EPOXY RESIN COMPOSITIONS ALBEMARLE CORPORATION (US) 2012-05-18 WO disclosed
CN-100545254-C Granular detergent composition and production method thereof LION CORP (JP) 2009-09-30 CN disclosed
CN-1748023-A Granular detergent composition and process for producing the same LION CORP (JP) 2006-03-15 CN disclosed
US-5635467-A COMPRISING SILICA BARRIER PARTICLES; CLEANING COMPOUND AMWAY CORPORATION (US) 1997-06-03 US disclosed
US-5496486-A BLENDING WITH SILICA BARRIER PARTICLES AMWAY CORPORATION (US) 1996-03-05 US disclosed
EP-0690123-A2 Process for increasing liquid surfactant loading in free flowing powder detergents Amway Corporation (US) 1996-01-03 EP disclosed
EP-0342043-B1 Granular laundry compositions PROCTER & GAMBLE (US) 1994-08-17 EP disclosed
US-5009804-A Minimized surfactant gel formation THE PROCTER & GAMBLE COMPANY (US) 1991-04-23 US disclosed
EP-0342043-A2 Granular laundry compositions THE PROCTER & GAMBLE COMPANY (US) 1989-11-15 EP disclosed
EP-0062523-B1 DETERGENT ADDITIVE COMPOSITIONS AND PREPARATIONS AND USE THEREOF IN DETERGENT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1987-12-09 EP disclosed
US-4399049-A PARTICLES EXTRUDED WITH ETHOXYLATED NONIONIC SURFACTANT; STORAGE STABILITY; RABID DISPERSION; LAUNDERING THE PROCTER & GAMBLE COMPANY (US) 1983-08-16 US disclosed
EP-0063017-A1 Detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1982-10-20 EP disclosed
EP-0062523-A2 Detergent additive compositions and preparations and use thereof in detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1982-10-13 EP disclosed
US-4347168-A ANIONIC, ALKOXYLATED NONIONIC AND QUATERNARY AMMONIUM CATIONIC SURFACTANTS THE PROCTER & GAMBLE COMPANY (US) 1982-08-31 US disclosed
EP-0051987-A1 Bleach activator compositions, preparation thereof and use in granular detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1982-05-19 EP disclosed
US-4321157-A SILICA OR SILICATE, ORGANIC PEROXY ACID BLEACH PRECURSOR, ALIPHATIC ALCOHOL-ALKYLENE OXIDE CONDENSATE NONIONIC SURFACTANT THE PROCTER & GAMBLE COMPANY (US) 1982-03-23 US disclosed
EP-0028432-A1 Granular laundry compositions THE PROCTER & GAMBLE COMPANY (US) 1981-05-13 EP disclosed
EP-0008829-A1 Controlled sudsing detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1980-03-19 EP disclosed
EP-0002084-A1 Granular detergent compositions for improved greasy soil removal THE PROCTER & GAMBLE COMPANY (US) 1979-05-30 EP disclosed
US-3933588-A IMMOBILIZED ENZYMES, LONG CHAIN QUATERNARY AMMONIUM COMPOUND STANDARD BRANDS INCORPORATED (US) 1976-01-20 US disclosed