Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4540254 | 0.91 | PTGER4 (0.41) | MAPK14MEN1KMT2APPARGNR2E3 | |
| SCHEMBL4538584 | 0.91 | GRM5 (0.43) | MAPK14MEN1KMT2APPARGNR2E3 | |
| SCHEMBL4538452 | 0.90 | PTGER4 (0.52) | MAPK14MEN1KMT2ACYP3A4PTGER4 | |
| SCHEMBL4544058 | 0.86 | MEN1 (0.59) | MAPK14MEN1KMT2APPARGNR2E3 | |
| SCHEMBL4540440 | 0.82 | MAPK14 (0.48) | MAPK14MEN1KMT2APPARGNR2E3 | |
| SCHEMBL4544036 | 0.79 | MEN1 (0.67) | MAPK14MEN1KMT2APPARGNR2E3 | |
| SCHEMBL4542706 | 0.79 | MEN1 (0.57) | MAPK14MEN1KMT2APPARGNR2E3 | |
| SCHEMBL4542354 | 0.78 | MEN1 (0.56) | MAPK14MEN1KMT2APPARGNR2E3 | |
| SCHEMBL4540706 | 0.78 | MEN1 (0.59) | MAPK14MEN1KMT2APPARGNR2E3 | |
| SCHEMBL4537119 | 0.77 | MEN1 (0.57) | MAPK14MEN1KMT2APPARGNR2E3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |