Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 15/20 | 0.88 |
| ▸ | TLR7 | Q9NYK1 | 10/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24052769 | 0.89 | TLR8 (0.88) | TLR8TLR7LMNA | |
| SCHEMBL24052759 | 0.88 | TLR8 (0.86) | TLR8TLR7LMNA | |
| SCHEMBL26100478 | 0.87 | TLR8 (0.83) | TLR8TLR7ADORA3 | |
| SCHEMBL25627724 | 0.84 | TLR8 (0.78) | TLR8TLR7LMNAMAOBADORA2A | |
| SCHEMBL25630769 | 0.83 | TLR8 (0.75) | TLR8TLR7 | |
| SCHEMBL25630795 | 0.83 | TLR8 (0.75) | TLR8TLR7LMNA | |
| SCHEMBL25630761 | 0.82 | TLR8 (0.74) | TLR8TLR7LMNA | |
| SCHEMBL4540442 | 0.82 | TLR8 (0.74) | TLR8TLR7ADORA3 | |
| SCHEMBL24052314 | 0.81 | TLR8 (0.73) | TLR8TLR7ADORA3 | |
| SCHEMBL25630901 | 0.81 | TLR8 (0.72) | TLR8TLR7CYP2C9CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125738-A1 | IMMUNE RESPONSE MODIFIER COMPOSITIONS AND METHODS | 3M Innovative Properties Company (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008079924-A1 | IMMUNE RESPONSE MODIFIER COMPOSITIONS AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-07-03 | — | — | WO | disclosed |