Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 17/20 | 0.83 |
| ▸ | TLR7 | Q9NYK1 | 12/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4540446 | 0.87 | TLR8 (0.88) | TLR8TLR7ADORA3 | |
| SCHEMBL24052769 | 0.87 | TLR8 (0.88) | TLR8TLR7 | |
| SCHEMBL24052759 | 0.86 | TLR8 (0.86) | TLR8TLR7 | |
| SCHEMBL24052314 | 0.85 | TLR8 (0.73) | TLR8TLR7MAPTNPSR1ADORA3 | |
| SCHEMBL4540442 | 0.83 | TLR8 (0.74) | TLR8TLR7ADORA3 | |
| SCHEMBL25627724 | 0.81 | TLR8 (0.78) | TLR8TLR7 | |
| SCHEMBL25628534 | 0.81 | TLR8 (0.69) | TLR8TLR7MAPTNPSR1ADORA3 | |
| SCHEMBL25627708 | 0.81 | TLR8 (0.69) | TLR8TLR7MAPTNPSR1ADORA3 | |
| SCHEMBL24052764 | 0.80 | TLR8 (0.72) | TLR8TLR7MAPTNPSR1 | |
| SCHEMBL5767925 | 0.80 | TLR8 (0.71) | TLR8TLR7ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023076848-A1 | PYRIDAZINEDIONE-BASED HETEROBICYCLIC COVALENT LINKERS AND METHODS AND APPLICATIONS THEREOF | SYNTABIO LLC (US) | 2023-05-04 | — | — | WO | disclosed |