Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 5/20 | 0.52 |
| ▸ | BRPF1 | P55201 | 14/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | BRD1 | O95696 | 8/20 | 0.34 |
| ▸ | BRD4 | O60885 | 4/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 4/20 | 0.34 |
| ▸ | BRPF3 | Q9ULD4 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4542551 | 0.87 | FASN (0.69) | FASNBRPF1ALOX5BRD1BRD4 | |
| SCHEMBL22206676 | 0.81 | FASN (0.48) | FASN | |
| SCHEMBL22206674 | 0.79 | FASN (0.48) | FASN | |
| SCHEMBL4566344 | 0.77 | FASN (0.45) | FASN | |
| SCHEMBL4562483 | 0.75 | FASN (0.55) | FASN | |
| SCHEMBL4562619 | 0.72 | FASN (0.68) | FASN | |
| SCHEMBL4538721 | 0.72 | FASN (0.79) | FASN | |
| SCHEMBL4538282 | 0.70 | FASN (0.76) | FASN | |
| SCHEMBL4560675 | 0.70 | FASN (0.70) | FASN | |
| SCHEMBL4543035 | 0.68 | FASN (1.00) | FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2637660-A1 | FATTY ACID SYNTHASE INHIBITORS | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2013-09-18 | — | — | EP | disclosed |
| WO-2012064642-A1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2012-05-18 | — | — | WO | disclosed |