SCHEMBL4540778

SCHEMBL4540778

CC(CN(C)C)OCCO

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
KCNH2 Q12809 1/20 0.36
MAPT P10636 1/20 0.33
PIK3CD O00329 1/20 0.33
TSHR P16473 2/20 0.33
ALDH1A1 P00352 1/20 0.31
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17069858 0.84 CYP3A4 (0.31) CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3
SCHEMBL15131750 0.82 ALDH1A1 (0.31) CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3
SCHEMBL18507949 0.82 TSHR (0.37) PIK3CDTSHR
SCHEMBL15215483 0.81 MAPT (0.31) MAPT
SCHEMBL11127496 0.79 SCN1A (0.36) ALDH1A1
SCHEMBL10881262 0.79 MAPT (0.40) MAPTALDH1A1
SCHEMBL6267588 0.78 TDP1 (0.31)
SCHEMBL13559689 0.78 KDM4E (0.33) CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3
SCHEMBL9250509 0.77 CHRM2 (0.42) CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3
SCHEMBL825846 0.77 PIK3CD (0.39) PIK3CDTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3891228-B1 HYDROPHILIC SILICA AND AQUEOUS DISPERSION CONTAINING SILANOL AND PAINT PREPARATION EVONIK OPERATIONS GMBH (DE) 2024-08-21 EP disclosed
CN-109627836-B Aqueous dispersion containing silica and trimethyl-1,6-hexamethylenediamine 赢创运营有限公司 2022-12-20 CN disclosed
CN-113166564-B Aqueous dispersion containing hydrophilic silica and silanol, and paint preparation 赢创运营有限公司 2022-06-07 CN disclosed
US-11352510-B2 Aqueous dispersion containing silicon dioxide and trimethyl-1,6-hexamethylendiamine EVONIK OPERATIONS GMBH (DE) 2022-06-07 US disclosed
EP-3467052-B1 AQUEOUS DISPERSION CONTAINING SILICON DIOXIDE AND TRIMETHYL 1.6-HEXAMETHYLENDIAMINE EVONIK OPERATIONS GMBH (DE) 2022-04-13 EP disclosed
US-11267975-B2 Hydrophilic aqueous dispersion containing silicon dioxide and silanol, and paint preparation EVONIK OPERATIONS GMBH (DE) 2022-03-08 US disclosed
US-20220041869-A1 Hydrophilic aqueous dispersion containing silicon dioxide and silanol, and paint preparation EVONIK OPERATIONS GMBH (DE) 2022-02-10 US disclosed
EP-3891228-A1 HYDROPHILIC AQUEOUS DISPERSION CONTAINING SILICON DIOXIDE AND SILANOL, AND PAINT PREPARATION Evonik Operations GmbH (DE) 2021-10-13 EP disclosed
CN-113166564-A Aqueous dispersion containing hydrophilic silica and silanol, and paint preparation 赢创运营有限公司 2021-07-23 CN disclosed
WO-2021072159-A1 ANODIC OXIDATION OF 5-AMINOURACIL MEDIBEACON INC. (US) 2021-04-15 WO disclosed
WO-2012062559-A1 DISPERSION COMPRISING HYDROPHOBIZED SILICON DIOXIDE PARTICLES, AND PAINT PREPARATION EVONIK DEGUSSA GMBH (DE) 2012-05-18 WO disclosed
EP-0984996-B1 RIGID POLYURETHANE FOAMS HUNTSMAN INT LLC (US) 2001-09-12 EP disclosed
EP-0984996-A1 RIGID POLYURETHANE FOAMS HUNTSMAN ICI CHEMICALS LLC (US) 2000-03-15 EP disclosed
US-5998494-A USING AMINOALCOHOL AS CATALYST IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1999-12-07 US disclosed
WO-1998054239-A1 RIGID POLYURETHANE FOAMS HUNTSMAN ICI CHEMICALS LLC (US) 1998-12-03 WO disclosed
US-4380591-A POLYESTER URETHANE COPOLYMER UNION CARBIDE CORPORATION (US) 1983-04-19 US disclosed
US-4379757-A Tertiary amine catalyst mixtures useful in cellular polyurethane formation UNION CARBIDE CORPORATION (US) 1983-04-12 US disclosed
EP-0048985-A1 Process for cellular polyurethane formation using tertiary amine catalyst mixtures UNION CARBIDE CORPORATION (US) 1982-04-07 EP disclosed
US-4122038-A DIMETHYLAMINO ETHER MONO-OL, TERTIARY AMINE UNION CARBIDE CORPORATION (US) 1978-10-24 US disclosed
US-4049931-A Catalyst systems containing dimethylamino ether mono-ols for polyurethane foam formation UNION CARBIDE CORPORATION (US) 1977-09-20 US disclosed