Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT1 | P04628 | 4/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 4/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13811897 | 0.86 | CSNK1D (0.51) | WNT1DYRK1AMEN1KMT2APARP1 | |
| SCHEMBL4080138 | 0.84 | CSNK1D (0.42) | WNT1DYRK1AFLT3 | |
| SCHEMBL4176018 | 0.82 | MAP2K4 (0.47) | DYRK1A | |
| SCHEMBL13812053 | 0.81 | KDM4E (0.57) | WNT1DYRK1APARP1HTR1AHTR3A | |
| SCHEMBL8252476 | 0.80 | DYRK1A (0.51) | WNT1DYRK1AMEN1KMT2APARP1 | |
| Hydrochloric Acid SCHEMBL4314527 | 0.79 | GLA (0.48) | WNT1DYRK1AMEN1KMT2APARP1 | |
| SCHEMBL5817740 | 0.78 | CSNK1D (0.46) | WNT1DYRK1A | |
| SCHEMBL4179665 | 0.77 | CSNK1D (0.46) | WNT1DYRK1A | |
| SCHEMBL4083131 | 0.76 | CSNK1D (0.45) | WNT1DYRK1AFLT3 | |
| SCHEMBL17801084 | 0.76 | ALDH1A1 (0.61) | WNT1DYRK1AMEN1KMT2APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2065383-A1 | Indazole compounds and methods of use thereof as protein kinase inhibitors | Signal Pharmaceuticals, Inc. (US) | 2009-06-03 | — | — | EP | disclosed |