Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4537985 | 0.88 | MAPT (0.62) | LMNAMAPTALDH1A1RAB9ATDP1 | |
| SCHEMBL8024498 | 0.85 | MAPT (0.53) | LMNAHTTMAPTALDH1A1RAB9A | |
| SCHEMBL5361493 | 0.84 | MAPT (0.70) | MAPTALDH1A1TDP1L3MBTL1PKM | |
| SCHEMBL16713330 | 0.84 | MAPT (0.56) | LMNAMAPTALDH1A1RAB9ATDP1 | |
| SCHEMBL12004226 | 0.84 | MAPT (0.56) | LMNAMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL15687598 | 0.83 | POLB (0.61) | LMNAMAPTALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL8033266 | 0.82 | MAPT (0.67) | LMNAHTTMAPTALDH1A1RAB9A | |
| SCHEMBL31072780 | 0.81 | KMT2A (0.50) | LMNAMAPTALDH1A1RAB9ATDP1 | |
| SCHEMBL28571322 | 0.81 | HTT (0.55) | LMNAHTTMAPTALDH1A1TDP1 | |
| SCHEMBL29343397 | 0.81 | KMT2A (0.50) | LMNAMAPTALDH1A1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |