Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 9/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31072780 | 1.00 | KMT2A (0.50) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL12004226 | 0.85 | MAPT (0.56) | KMT2AMEN1MAPTALDH1A1RAB9A | |
| SCHEMBL4537985 | 0.85 | MAPT (0.62) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL8024498 | 0.85 | MAPT (0.53) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL29342739 | 0.85 | MAPT (0.59) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL31072813 | 0.85 | MAPT (0.59) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL29343403 | 0.82 | MAPT (0.49) | MAPTALDH1A1LMNAPTGER4GAA | |
| SCHEMBL4542148 | 0.81 | LMNA (0.53) | KMT2AMEN1MAPTALDH1A1RAB9A | |
| SCHEMBL5361493 | 0.81 | MAPT (0.70) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL28544871 | 0.81 | HTT (0.53) | KMT2AMEN1MAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151519-A2 | PPARG MODULATORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATIN, INCORPORATED (US) | 2024-07-18 | — | — | WO | disclosed |