Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 3/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4129353 | 0.89 | PKM (0.48) | PKMCYP4F2CYP4A11USP2SMN1; SMN2 | |
| SCHEMBL27236283 | 0.81 | PKM (0.44) | PKMCYP4F2CYP4A11USP2SMN1; SMN2 | |
| SCHEMBL6188518 | 0.81 | USP2 (0.42) | PKMCYP4F2CYP4A11USP2SMN1; SMN2 | |
| SCHEMBL21963889 | 0.80 | PKM (0.47) | PKMCYP4F2CYP4A11USP2SMN1; SMN2 | |
| SCHEMBL3970403 | 0.80 | PKM (0.49) | PKMCYP4F2CYP4A11USP2SMN1; SMN2 | |
| SCHEMBL17020479 | 0.80 | PKM (0.44) | PKMCYP4F2CYP4A11USP2SMN1; SMN2 | |
| SCHEMBL16986998 | 0.77 | PKM (0.49) | PKMCYP4F2CYP4A11USP2SMN1; SMN2 | |
| SCHEMBL4295685 | 0.77 | PKM (0.49) | PKMCYP4F2CYP4A11USP2SMN1; SMN2 | |
| SCHEMBL3960309 | 0.77 | CYP2D6 (0.46) | USP2 | |
| SCHEMBL8263471 | 0.76 | PKM (0.41) | PKMCYP4F2CYP4A11USP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013197-A1 | PHENETHANOLAMINE DERIVATIVES AS BETA2 ADRENORECEPTOR AGONISTS | AstraZeneca AB (SE) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007102771-A1 | PHENETHANOLAMINE DERIVATIVES AS BETA2 ADRENORECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2007-09-13 | — | — | WO | disclosed |