Norvaline

Norvaline

SCHEMBL4543134

CCC[C@H](N)C(=O)O.CSCC[C@H](N)C(=O)NO

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 2/20 0.42
NOS1 P29475 2/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
HDAC9 Q9UKV0 1/20 0.42
HDAC5 Q9UQL6 1/20 0.42
BHMT Q93088 7/20 0.41
BHMT2 Q9H2M3 1/20 0.41
GRIK1 P39086 1/20 0.41
SLC1A3 P43003 1/20 0.41
SLC1A2 P43004 1/20 0.41
SLC1A1 P43005 1/20 0.41
GRIK2 Q13002 1/20 0.41
RNPEP Q9H4A4 1/20 0.40
NOS2 P35228 2/20 0.39
DPP4 P27487 1/20 0.38
DPP8 Q6V1X1 1/20 0.38
DPP9 Q86TI2 1/20 0.38
DPP7 Q9UHL4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methionine SCHEMBL11179579 0.88 BHMT (0.50) NOS3NOS1BHMTBHMT2GRIK1
Racemethionine SCHEMBL11179574 0.88 BHMT (0.50) NOS3NOS1BHMTBHMT2GRIK1
SCHEMBL1920676 0.87 CTSC (0.41) NOS3NOS1HDAC7HDAC8HDAC6
SCHEMBL1896269 0.87 CTSC (0.41) NOS3NOS1HDAC7HDAC8HDAC6
SCHEMBL3686360 0.87 CTSC (0.41) NOS3NOS1HDAC7HDAC8HDAC6
Hydrochloric Acid SCHEMBL3458427 0.85 CTSC (0.40) NOS3NOS1HDAC7HDAC8HDAC6
Hydrochloric Acid SCHEMBL3458429 0.85 CTSC (0.40) NOS3NOS1HDAC7HDAC8HDAC6
Hydrochloric Acid SCHEMBL2253202 0.85 CTSC (0.40) NOS3NOS1HDAC7HDAC8HDAC6
Racemethionine SCHEMBL8714479 0.83 BHMT (0.52) NOS3NOS1BHMTBHMT2GRIK1
Norleucine SCHEMBL12485007 0.82 SLC1A2 (0.50) NOS3NOS1BHMTBHMT2GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4347766-A1 MACHINE DISHWASH DETERGENT Unilever IP Holdings B.V. (NL) 2024-04-10 EP disclosed
WO-2022253565-A1 MACHINE DISHWASH DETERGENT UNILEVER IP HOLDINGS B.V. (NL) 2022-12-08 WO disclosed
EP-2688995-A1 METHOD OF CLEANING LAUNDRY Unilever NV (NL) 2014-01-29 EP disclosed
WO-2012126801-A1 METHOD OF CLEANING LAUNDRY UNILEVER NV (NL) 2012-09-27 WO disclosed
WO-2012062566-A1 LAUNDRY DETERGENT COMPOSITION UNILEVER NV (NL) 2012-05-18 WO disclosed