Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 6/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | CTSA | P10619 | 3/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 2/20 | 0.38 |
| ▸ | FLT3 | P36888 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1616804 | 0.90 | FGFR1 (0.41) | FGFR1SRCBACE1KDRCTSA | |
| SCHEMBL1616701 | 0.90 | FGFR1 (0.41) | FGFR1SRCBACE1KDRCTSA | |
| SCHEMBL1617239 | 0.90 | FGFR1 (0.41) | FGFR1SRCBACE1KDRCTSA | |
| SCHEMBL1617275 | 0.86 | NR3C1 (0.40) | FGFR1SRCBACE1KDRCTSA | |
| SCHEMBL12415806 | 0.85 | FGFR1 (0.52) | FGFR1SRCBACE1KDRGABRA1 | |
| SCHEMBL1616915 | 0.85 | FGFR1 (0.44) | FGFR1SRCCTSAMAPK1SMN1; SMN2 | |
| SCHEMBL1761747 | 0.83 | CNR1 (0.41) | FGFR1SRCKDRCTSAGABRA1 | |
| SCHEMBL1616268 | 0.83 | FGFR1 (0.41) | FGFR1SRCKDRCTSAGABRA1 | |
| SCHEMBL1761975 | 0.83 | CNR1 (0.41) | FGFR1SRCKDRCTSAGABRA1 | |
| SCHEMBL1617150 | 0.83 | FGFR1 (0.41) | FGFR1SRCKDRCTSAGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996556-B1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE FOR MODULATING THE GABAA RECEPTOR COMPLEX | NEUROSEARCH AS (DK) | 2009-11-18 | — | — | EP | disclosed |