Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.35 |
| ▸ | CCKBR | P32239 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL392779 | 0.77 | CYP11B1 (0.43) | CYP11B1CYP11B2KMT2AKCNN4KCNA3 | |
| SCHEMBL5240188 | 0.77 | CYP11B1 (0.43) | CYP11B1CYP11B2KMT2AKCNN4KCNA3 | |
| SCHEMBL2279828 | 0.77 | CYP11B1 (0.43) | CYP11B1CYP11B2KMT2AKCNN4KCNA3 | |
| SCHEMBL584588 | 0.77 | CYP11B1 (0.43) | CYP11B1CYP11B2KMT2AKCNN4KCNA3 | |
| SCHEMBL27685085 | 0.77 | CYP11B1 (0.43) | CYP11B1CYP11B2KMT2AKCNN4KCNA3 | |
| SCHEMBL10915007 | 0.77 | CYP11B1 (0.43) | CYP11B1CYP11B2KMT2AKCNN4KCNA3 | |
| SCHEMBL4022590 | 0.77 | CYP11B1 (0.40) | CYP11B1CYP11B2KMT2AKCNN4KCNA3 | |
| SCHEMBL1532332 | 0.74 | CYP11B1 (0.41) | CYP11B1CYP11B2KMT2AKCNN4KCNA3 | |
| SCHEMBL27544681 | 0.74 | KMT2A (0.41) | CYP11B1CYP11B2KMT2AKCNN4KCNA3 | |
| SCHEMBL6948425 | 0.73 | KMT2A (0.43) | CYP11B1CYP11B2KMT2AKCNN4KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1840125-B1 | Intermediates for the preparation of dioxane-2-alkyl carbamates | SANOFI AVENTIS (FR) | 2009-06-24 | — | — | EP | disclosed |
| EP-1537096-B1 | DERIVATIVES OF DIOXANE-2-ALKYL CARBAMATES, PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2008-09-24 | — | — | EP | disclosed |
| EP-1840125-A2 | Derivatives of dioxane-2-alkyl carbamates, preparation thereof and application thereof in therapeutics | sanofi-aventis (FR) | 2007-10-03 | — | — | EP | disclosed |
| EP-1537096-A2 | DERIVATIVES OF DIOXANE-2-ALKYL CARBAMATES, PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004020430-A2 | DERIVATIVES OF DIOXANE-2-ALKYL CARBAMATES, PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2004-03-11 | — | — | WO | disclosed |