SCHEMBL4544098

SCHEMBL4544098

C=CCOC(CO)OCC=C

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18107067 0.85
SCHEMBL9003015 0.79 TSHR (0.32) TSHRCA1CA2CA7
SCHEMBL18810743 0.79
SCHEMBL87994 0.78
SCHEMBL11252398 0.77 CA1 (0.32) CA1CA2CA7CA9
SCHEMBL38369 0.76
SCHEMBL9003134 0.75
SCHEMBL7077632 0.74 ALDH1A1 (0.37) CA1CA2CA7CA9
SCHEMBL14938319 0.74 CA1 (0.31) CA1CA2CA7CA9
SCHEMBL5500894 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1870735-B1 Wettable silicone hydrogel contact lenses and related compositions and methods COOPERVISION INT HOLDING CO LP (BB) 2009-03-18 EP claimed
EP-1592395-B1 ANTIPERSPIRANT COMPOSITIONS UNILEVER PLC (GB) 2007-08-08 EP claimed
EP-0937111-B1 CROSS-LINKABLE COMPOSITIONS CONTAINING FUNCTIONALIZED SILICON FLUIDS AND USE OF THESE COMPOSITIONS FOR PREPARING POLYURETHANE FILMS RHODIA CHIMIE SA (FR) 2004-01-28 EP disclosed
EP-0755960-B1 Polyfunctional perfluorinated polyorganosiloxanes and processes for their preparation RHODIA CHIMIE SA (FR) 2002-11-27 EP disclosed
EP-0937111-A1 CROSS-LINKABLE COMPOSITIONS CONTAINING FUNCTIONALIZED SILICON FLUIDS AND USE OF THESE COMPOSITIONS FOR PREPARING POLYURETHANE FILMS RHODIA CHIMIE (FR) 1999-08-25 EP disclosed
WO-1998021257-A1 CROSS-LINKABLE COMPOSITIONS CONTAINING FUNCTIONALIZED SILICON FLUIDS AND USE OF THESE COMPOSITIONS FOR PREPARING POLYURETHANE FILMS RHODIA CHIMIE (FR) 1998-05-22 WO disclosed
EP-0755960-A1 Polyfunctional perhalogenated polyorganosiloxanes and processes for their preparation RHONE-POULENC CHIMIE (FR) 1997-01-29 EP disclosed
EP-0369394-B1 POLYETHER IMPRESSION MATERIAL, PROCESS FOR ITS PREPARATION AND ITS USE THERA Patent GmbH & Co. KG Gesellschaft für industrielle Schutzrechte (DE) 1993-08-11 EP disclosed
US-5086148-A Dentistry ESPE STIFTUNG & CO., PRODUKTIONS - UND VERTRIEBS KG (DE) 1992-02-04 US disclosed
EP-0396444-A1 Curable fluorinated copolymers, their method of preparation and their use in lacquers and paints ELF ATOCHEM S.A. (FR) 1990-11-07 EP disclosed
EP-0369394-A2 Polyether impression material, process for its preparation and its use THERA Patent GmbH & Co. KG Gesellschaft für industrielle Schutzrechte (DE) 1990-05-23 EP disclosed