⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748624 | 0.81 | TAAR1 (0.63) | — | |
| SCHEMBL9200966 | 0.79 | TAAR1 (0.60) | — | |
| SCHEMBL4399626 | 0.79 | TAAR1 (0.74) | — | |
| SCHEMBL3133598 | 0.78 | TAAR1 (0.54) | — | |
| Bromide SCHEMBL3514625 | 0.78 | TAAR1 (0.54) | — | |
| SCHEMBL29353789 | 0.77 | — | — | |
| SCHEMBL6882 | 0.77 | — | — | |
| SCHEMBL42451 | 0.75 | — | — | |
| Bromide SCHEMBL3514628 | 0.75 | TAAR1 (0.56) | — | |
| SCHEMBL15580376 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038272-A2 | PYRIDINONYL PDK1 INHIBITORS | Sunesis Pharmaceuticals, Inc. (US) | 2009-03-25 | — | — | EP | disclosed |
| EP-1976829-A2 | N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 2008-10-08 | — | — | EP | disclosed |
| WO-2008005457-A2 | PYRIDINONYL PDK1 INHIBITORS | SUNESIS PHARMACEUTICALS (US) | 2008-01-10 | — | — | WO | disclosed |
| WO-2007070556-A2 | N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 2007-06-21 | — | — | WO | disclosed |
| WO-1999064379-A2 | BIOMIMETIC COMBINATORIAL SYNTHESIS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1999-12-16 | — | — | WO | disclosed |