Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGPAT2 | O15120 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 7/20 | 0.41 |
| ▸ | RAB9A | P51151 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LATS1 | O95835 | 2/20 | 0.39 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1024010 | 0.88 | ESR1 (0.44) | AGPAT2ESR1ESR2NPC1RAB9A | |
| SCHEMBL1023943 | 0.88 | ESR1 (0.44) | AGPAT2ESR1ESR2NPC1RAB9A | |
| SCHEMBL1027432 | 0.88 | NPC1 (0.46) | AGPAT2ESR1ESR2NPC1RAB9A | |
| SCHEMBL1026561 | 0.88 | AGPAT2 (0.52) | AGPAT2ESR1ESR2NPC1RAB9A | |
| SCHEMBL4544429 | 0.80 | PIK3CB (0.56) | NPC1RAB9AMAPTSMN1; SMN2TP53 | |
| SCHEMBL1024114 | 0.80 | HSD17B10 (0.46) | ESR1ESR2NPC1RAB9AMAPT | |
| SCHEMBL4544387 | 0.79 | KDM4E (0.54) | AGPAT2ESR1ESR2NPC1RAB9A | |
| SCHEMBL1026580 | 0.78 | ESR1 (0.43) | AGPAT2ESR1ESR2NPC1RAB9A | |
| SCHEMBL1025131 | 0.76 | NPC1 (0.44) | AGPAT2NPC1RAB9AKDM4ECYP1A2 | |
| SCHEMBL1025684 | 0.76 | ESR2 (0.40) | AGPAT2ESR1ESR2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130190271-A1 | FUSED HETEROCYCLIC COMPOUNDS AND USES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-07-25 | — | — | US | disclosed |
| US-8445522-B2 | Substituted 2-(4-pyridyl)benzoxazoles, and compositions thereof, for use in arthropod pest control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-05-21 | — | — | US | disclosed |
| US-8324387-B2 | Substituted Oxazolo[5,4-b]pyridines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-12-04 | — | — | US | disclosed |
| US-20120264750-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-18 | — | — | US | disclosed |
| US-20120252803-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-04 | — | — | US | disclosed |
| US-20120252804-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-04 | — | — | US | disclosed |
| US-20120245167-A1 | ARTHROPOD PEST CONTROL METHOD AND COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-09-27 | — | — | US | disclosed |
| US-20120245159-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-09-27 | — | — | US | disclosed |
| US-8242133-B2 | Arthropod pest control compositions comprising substituted oxazolo [5,4-b ] pyridines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-14 | — | — | US | disclosed |
| US-20120108586-A1 | ARTHROPOD PEST CONTROL METHOD AND COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-05-03 | — | — | US | disclosed |
| US-20110039843-A1 | HARMFUL ARTHROPOD CONTROL COMPOSITION, AND FUSED HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245167-A1 | ARTHROPOD PEST CONTROL METHOD AND COMPOSITION | C5, C1S, C1R | AGPAT2 652/4885ESR1 3274/4885ESR2 2840/4885 |
| US-20120108586-A1 | ARTHROPOD PEST CONTROL METHOD AND COMPOSITION | C5, C1S, C1R | AGPAT2 652/4885ESR1 3274/4885ESR2 2840/4885 |
| US-20120264750-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | DDT, ACHE, AADAC | AGPAT2 1499/4885ESR1 4830/4885ESR2 4739/4885 |
| US-20120245159-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | NISCH, DDT, AADAC | AGPAT2 2123/4885ESR1 4496/4885ESR2 4454/4885 |
| US-20110039843-A1 | HARMFUL ARTHROPOD CONTROL COMPOSITION, AND FUSED HETEROCYCLIC COMPOUND | C5, C9, C1S | AGPAT2 1148/4885ESR1 2040/4885ESR2 2609/4885 |
| US-20130190271-A1 | FUSED HETEROCYCLIC COMPOUNDS AND USES THEREOF | CYC1, C9, C5 | AGPAT2 1407/4885ESR1 1513/4885ESR2 1544/4885 |
| US-20120252803-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | DDT, ACHE, AADAC | AGPAT2 868/4885ESR1 4775/4885ESR2 4545/4885 |
| US-20120252804-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | DDT, AADAC, CYP4F3 | AGPAT2 1650/4885ESR1 4621/4885ESR2 4393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.