Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 5/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 2/20 | 0.35 |
| ▸ | KLK7 | P49862 | 2/20 | 0.35 |
| ▸ | KLK14 | Q9P0G3 | 2/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 7/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1026787 | 0.88 | AAK1 (0.41) | CTSGKLK7KLK14KLK5MAPT | |
| SCHEMBL1024638 | 0.87 | CYP17A1 (0.34) | AAK1 | |
| SCHEMBL1026065 | 0.85 | AAK1 (0.35) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1025032 | 0.83 | KDM4E (0.37) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1024043 | 0.80 | F7 (0.39) | NPSR1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL1024619 | 0.79 | ESR1 (0.39) | NPSR1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL4544464 | 0.78 | HPGD (0.54) | S1PR1S1PR3MAPTKDM4EALDH1A1 | |
| SCHEMBL4544465 | 0.78 | S1PR1 (0.45) | S1PR1S1PR3CTSGKLK7KLK14 | |
| SCHEMBL1025727 | 0.77 | AGPAT2 (0.45) | S1PR1S1PR3MAPTKDM4EALDH1A1 | |
| SCHEMBL4544459 | 0.76 | F2RL3 (0.42) | S1PR1S1PR3MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130190271-A1 | FUSED HETEROCYCLIC COMPOUNDS AND USES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-07-25 | — | — | US | disclosed |
| US-8445522-B2 | Substituted 2-(4-pyridyl)benzoxazoles, and compositions thereof, for use in arthropod pest control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-05-21 | — | — | US | disclosed |
| US-8324387-B2 | Substituted Oxazolo[5,4-b]pyridines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-12-04 | — | — | US | disclosed |
| US-20120264750-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-18 | — | — | US | disclosed |
| US-20120252804-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-04 | — | — | US | disclosed |
| US-20120252803-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-04 | — | — | US | disclosed |
| US-20120245167-A1 | ARTHROPOD PEST CONTROL METHOD AND COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-09-27 | — | — | US | disclosed |
| US-20120245159-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-09-27 | — | — | US | disclosed |
| US-8242133-B2 | Arthropod pest control compositions comprising substituted oxazolo [5,4-b ] pyridines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-14 | — | — | US | disclosed |
| US-20120108586-A1 | ARTHROPOD PEST CONTROL METHOD AND COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-05-03 | — | — | US | disclosed |
| US-20110039843-A1 | HARMFUL ARTHROPOD CONTROL COMPOSITION, AND FUSED HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245167-A1 | ARTHROPOD PEST CONTROL METHOD AND COMPOSITION | C5, C1S, C1R | S1PR1 2804/4885S1PR3 3317/4885CTSG 2258/4885 |
| US-20120108586-A1 | ARTHROPOD PEST CONTROL METHOD AND COMPOSITION | C5, C1S, C1R | S1PR1 2804/4885S1PR3 3317/4885CTSG 2258/4885 |
| US-20120264750-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | DDT, ACHE, AADAC | S1PR1 3862/4885S1PR3 3939/4885CTSG 1350/4885 |
| US-20120245159-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | NISCH, DDT, AADAC | S1PR1 4086/4885S1PR3 3583/4885CTSG 1509/4885 |
| US-20110039843-A1 | HARMFUL ARTHROPOD CONTROL COMPOSITION, AND FUSED HETEROCYCLIC COMPOUND | C5, C9, C1S | S1PR1 3849/4885S1PR3 4126/4885CTSG 1299/4885 |
| US-20130190271-A1 | FUSED HETEROCYCLIC COMPOUNDS AND USES THEREOF | CYC1, C9, C5 | S1PR1 3920/4885S1PR3 4135/4885CTSG 1400/4885 |
| US-20120252803-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | DDT, ACHE, AADAC | S1PR1 3832/4885S1PR3 2831/4885CTSG 1342/4885 |
| US-20120252804-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | DDT, AADAC, CYP4F3 | S1PR1 3369/4885S1PR3 2801/4885CTSG 2313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.